2023
Endoscopic Ultrasound in Cancer Staging
Aslanian H, Muniraj T, Nagar A, Parsons D. Endoscopic Ultrasound in Cancer Staging. Gastrointestinal Endoscopy Clinics Of North America 2023, 34: 37-49. PMID: 37973230, DOI: 10.1016/j.giec.2023.09.009.Peer-Reviewed Original Research
2021
Prevalence of Advanced Colorectal Neoplasia in Veterans
Imperiale TF, Daggy JK, Imler TD, Sherer EA, Kahi CJ, Larson J, Cardwell J, Johnson CS, Ahnen DJ, Antaki F, Ashley C, Baffy G, Dominitz JA, Hou J, Korsten MA, Nagar A, Promrat K, Robertson DJ, Saini S, Shergill A, Smalley WE. Prevalence of Advanced Colorectal Neoplasia in Veterans. Journal Of Clinical Gastroenterology 2021, 55: 876-883. PMID: 34049372, DOI: 10.1097/mcg.0000000000001402.Peer-Reviewed Original ResearchConceptsAdvanced neoplasiaProximal colorectal cancerColorectal cancerVeterans Affairs Medical CenterProximal advanced neoplasiaAdvanced colorectal neoplasiaCross-sectional studyIndependent effectsHigh overall prevalenceRace/ethnicityCRC prevalenceColorectal neoplasiaCRC riskOverall prevalenceMedical CenterDiagnostic subgroupsLogistic regressionPrevalenceAgeVeteransWomenColonoscopyNeoplasiaRiskAdvanced findingsImpact of Neoadjuvant Chemotherapy and Pretreatment Biliary Drainage for Pancreatic Head Ductal Adenocarcinoma
Saffo S, Peng C, Salem R, Taddei T, Nagar A. Impact of Neoadjuvant Chemotherapy and Pretreatment Biliary Drainage for Pancreatic Head Ductal Adenocarcinoma. Digestive Diseases And Sciences 2021, 67: 1409-1416. PMID: 33811566, PMCID: PMC8487432, DOI: 10.1007/s10620-021-06967-7.Peer-Reviewed Original ResearchConceptsNeoadjuvant chemotherapyBiliary drainageDuctal adenocarcinomaSingle-center cohort studyHigh-volume tertiary centerPancreatic head ductal adenocarcinomaBackgroundPancreatic ductal adenocarcinomaUse of chemotherapyMultidisciplinary treatment modelCancer-related deathImplementation of guidelinesDelivery of careElectronic medical recordsResectable diseaseCohort studySurgical complicationsSurvival benefitTertiary centerPostprocedure complicationsPreoperative jaundiceAppropriate indicationsMedical recordsTherapeutic endoscopistsOutcome dataPractice trends
2015
Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men
Clark BT, Protiva P, Nagar A, Imaeda A, Ciarleglio MM, Deng Y, Laine L. Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men. Gastroenterology 2015, 150: 396-405. PMID: 26439436, PMCID: PMC4728019, DOI: 10.1053/j.gastro.2015.09.041.Peer-Reviewed Original ResearchConceptsAdequate bowel preparationBBPS scoreSurveillance colonoscopyBowel preparationColon segmentsBBPS scoresSecond examinationWest Haven Veterans Affairs Medical CenterVeterans Affairs Medical CenterFirst examinationGuideline-recommended intervalsProspective observational studyDetection of adenomasIdentification of polypsColonoscopic evaluationPrimary outcomeSurveillance intervalsBlinded endoscopistsColonoscopy examinationObservational studyPrEP scaleMedical CenterInitial examinationStudy subjectsAdequate preparationMulti-Center Colonoscopy Quality Measurement Utilizing Natural Language Processing
Imler TD, Morea J, Kahi C, Sherer EA, Cardwell J, Johnson CS, Xu H, Ahnen D, Antaki F, Ashley C, Baffy G, Cho I, Dominitz J, Hou J, Korsten M, Nagar A, Promrat K, Robertson D, Saini S, Shergill A, Smalley W, Imperiale TF. Multi-Center Colonoscopy Quality Measurement Utilizing Natural Language Processing. The American Journal Of Gastroenterology 2015, 110: 543. PMID: 25756240, DOI: 10.1038/ajg.2015.51.Peer-Reviewed Original ResearchConceptsNatural language processingSurveillance intervalsHyperplastic polypsColorectal cancer screeningColonoscopy surveillance intervalsLarge hyperplastic polypsNumber of adenomasAdenoma detection rateSmall hyperplastic polypsSessile serrated polypsColonoscopy quality measuresLanguage processingManual reviewColonoscopy findingsAdvanced adenomasPrimary outcomePathologic findingsPathology recordsCancer screeningSerrated polypsLesion locationColonoscopy qualityExpert manual review
2014
Bleeding From a Duodenal Varix
Kinzel J, Pichetshote N, Dredar S, Aslanian H, Nagar A. Bleeding From a Duodenal Varix. Journal Of Clinical Gastroenterology 2014, 48: 362-364. PMID: 24518801, DOI: 10.1097/mcg.0000000000000004.Peer-Reviewed Original ResearchConceptsClass C cirrhosisDuodenal varicesEmbolization coilsChild's class C cirrhosisTransjugular intrahepatic portosystemic shuntIntrahepatic portosystemic shuntEUS-guided placementC cirrhosisCyanoacrylate injectionEctopic varicesInitial endoscopyPortosystemic shuntEndoscopic ultrasoundVaricesVariceal hemostasisExcellent hemostasisHemostasisAdvantageous modalityInjectionHematemesisCirrhosisPatientsEndoscopySubsequent attemptsShunt
2010
Barrett's Surveillance Identifies Patients with Early Esophageal Adenocarcinoma
Wong T, Tian J, Nagar AB. Barrett's Surveillance Identifies Patients with Early Esophageal Adenocarcinoma. The American Journal Of Medicine 2010, 123: 462-467. PMID: 20399324, DOI: 10.1016/j.amjmed.2009.10.013.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseaseEsophageal adenocarcinomaBarrett's esophagusSurveillance programReflux diseaseBarrett's surveillanceBarrett's surveillance programEarly esophageal adenocarcinomaHigh-grade dysplasiaDevelopment of dysplasiaRetrospective study designProgression of metaplasiaRisk of cancerUpper endoscopic proceduresInstitutional review boardBarrett's cohortSurveillance endoscopyMore patientsRetrospective reviewEndoscopic surveillanceBarrett's segmentSurveillance groupSurveillance periodEndoscopic proceduresNew diagnosis
2008
Prevention of post-ERCP pancreatitis: a little antacid might go a long way
Nagar AB, Gorelick F. Prevention of post-ERCP pancreatitis: a little antacid might go a long way. Gut 2008, 57: 1492. PMID: 18941003, DOI: 10.1136/gut.2008.157289.Peer-Reviewed Original ResearchEthanol Exposure Depletes Hepatic Pigment Epithelium-Derived Factor, a Novel Lipid Regulator
Chung C, Shugrue C, Nagar A, Doll JA, Cornwell M, Gattu A, Kolodecik T, Pandol SJ, Gorelick F. Ethanol Exposure Depletes Hepatic Pigment Epithelium-Derived Factor, a Novel Lipid Regulator. Gastroenterology 2008, 136: 331-340.e2. PMID: 18996124, PMCID: PMC2833423, DOI: 10.1053/j.gastro.2008.09.065.Peer-Reviewed Original ResearchConceptsPigment epithelium-derived factorEthanol-induced hepatic steatosisEthanol-induced steatosisMMP-2/9 activityPEDF levelsHepatic steatosisEthanol feedingLoss of PEDFAnimal modelsTriglyceride contentRecombinant pigment epithelium-derived factorNovel lipid regulatorLiver triglyceride contentLiver biopsy specimensEpithelium-derived factorEthanol fed animalsNormal liver samplesAccumulation of lipidsHistologic steatosisBiopsy specimensClinical studiesEthanol exposureHepatocellular carcinomaSteatosisPigment epithelium
2007
Isolated colonic ulcers: Diagnosis and management
Nagar AB. Isolated colonic ulcers: Diagnosis and management. Current Gastroenterology Reports 2007, 9: 422-428. PMID: 17991345, DOI: 10.1007/s11894-007-0053-9.Peer-Reviewed Original ResearchConceptsSolitary rectal ulcer syndromeNonsteroidal anti-inflammatory drugsManagement of constipationChronic gastrointestinal bleedingInflammatory bowel diseaseAnti-inflammatory drugsColonic ulcersNonspecific ulcersRectal ulcerStercoral ulcerationAbdominal painFecal impactionGastrointestinal bleedingColonic perforationAppropriate patientsBowel diseaseColonic ulcerationInfectious causesRight colonCertain infectionsUlcer syndromeIncidental findingCommon causeIsolated ulcerUlcers