1997
Glutamate-Dependent Phosphorylation of Elongation Factor-2 and Inhibition of Protein Synthesis in Neurons
Marin P, Nastiuk K, Daniel N, Girault J, Czernik A, Glowinski J, Nairn A, Prémont J. Glutamate-Dependent Phosphorylation of Elongation Factor-2 and Inhibition of Protein Synthesis in Neurons. Journal Of Neuroscience 1997, 17: 3445-3454. PMID: 9133370, PMCID: PMC6573691, DOI: 10.1523/jneurosci.17-10-03445.1997.Peer-Reviewed Original ResearchMeSH Keywords6-Cyano-7-nitroquinoxaline-2,3-dioneAnimalsAntibody SpecificityCalciumCell SurvivalCells, CulturedCerebral CortexDizocilpine MaleateExcitatory Amino Acid AntagonistsGlutamic AcidMiceNerve Tissue ProteinsNeuronsNeurotoxinsPeptide Elongation Factor 2Peptide Elongation FactorsPhosphorylationProtein BiosynthesisProtein Synthesis InhibitorsReceptors, AMPAReceptors, N-Methyl-D-AspartateConceptsNeuronal deathEukaryotic elongation factor 2Factor 2Cortical neuronsElongation factor 2Glutamate receptorsProtective effectLong-term effectsProtein synthesisPersistent inhibitionPharmacological analysisPharmacological inhibitionCytosolic Ca2Phosphorylation state-specific antibodiesNeuronsNMDAGlutamateInhibitionProtein translationDeathPhosphorylationClose correlationTransient phosphorylationCa2Excitotoxicity
1991
[23] Production of phosphorylation state-specific antibodies
Jczernik A, Girault J, Nairn A, Chen J, Snyder G, Kebabian J, Greengard P. [23] Production of phosphorylation state-specific antibodies. Methods In Enzymology 1991, 201: 264-283. PMID: 1943769, DOI: 10.1016/0076-6879(91)01025-w.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibodiesAntibodies, MonoclonalAntibody SpecificityCross ReactionsElectrophoresis, Polyacrylamide GelEnzyme-Linked Immunosorbent AssayGTP-Binding ProteinsImmunoblottingKineticsMolecular Sequence DataPeptidesPhosphopeptidesPhosphoproteinsPhosphorylationRabbitsRecombinant ProteinsSynapsins
1982
Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein
Nairn A, Detre J, Casnellie J, Greengard P. Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein. Nature 1982, 299: 734-736. PMID: 6289133, DOI: 10.1038/299734a0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibody SpecificityCerebellumCyclic GMPNerve Tissue ProteinsPhosphoproteinsProtein KinasesRabbitsRadioimmunoassayStructure-Activity Relationship