Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.
Hvalby O, Hemmings H, Paulsen O, Czernik A, Nairn A, Godfraind J, Jensen V, Raastad M, Storm J, Andersen P. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 4761-4765. PMID: 8197132, PMCID: PMC43868, DOI: 10.1073/pnas.91.11.4761.Peer-Reviewed Original ResearchConceptsProtein kinase CProtein kinase inhibitor peptideProtein kinase inhibitionInhibitor peptideDependent protein kinase IIInhibition of PKCKinase inhibitionProtein kinase IIPseudosubstrate domainAutoregulatory domainProtein kinasePhysiological assaysKinase IIKinase CLong-term potentiationSynthetic peptide analoguesInductionPeptide analoguesHippocampal neuronsPeptidesIntracellular deliveryBlockade of inductionInduction of LTPInhibitionVitro