2000
Novel compounds, ‘1,3-selenazine derivatives’ as specific inhibitors of eukaryotic elongation factor-2 kinase
Cho S, Koketsu M, Ishihara H, Matsushita M, Nairn A, Fukazawa H, Uehara Y. Novel compounds, ‘1,3-selenazine derivatives’ as specific inhibitors of eukaryotic elongation factor-2 kinase. Biochimica Et Biophysica Acta 2000, 1475: 207-215. PMID: 10913818, DOI: 10.1016/s0304-4165(00)00061-1.Peer-Reviewed Original ResearchConceptsV-src-transformed NIH3T3 cellsEukaryotic elongation factor 2 kinaseProtein kinase AElongation factor 2 kinaseProtein kinase CProtein tyrosine kinasesEEF-2KProtein kinaseEEF-2K inhibitorNIH3T3 cellsCalmodulin-dependent protein kinaseV-Src kinaseMultiple protein kinasesCalmodulin-dependent protein kinase IIProtein levelsK inhibitorsProtein kinase IIEEF-2K.Kinase AKinase IITyrosine kinaseKinase CKinaseTs-4Specific inhibitor
1995
EF2K Elongation factor-2 kinase (vertebrates) (CaM-dependent PK III)
Nairn A. EF2K Elongation factor-2 kinase (vertebrates) (CaM-dependent PK III). 1995, 135-136. DOI: 10.1016/b978-012324719-3/50031-5.Peer-Reviewed Original ResearchElongation factor 2EF-2 kinaseElongation factor 2 kinaseYeast EF-2Factor 2EF2KMammalian enzymeSDS-PAGE systemDependent regulationRabbit reticulocytesSubunit sizeExact functionReticulocyte enzymeDifferent isoformsPolypeptide chainProtein synthesisKinaseCell proliferationSame affinityGrowth factorEnzymeDependent inhibitionPhosphorylatesIntracellular calciumCa2