cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones
Paupardin-Tritsch D, Hammond C, Gerschenfeld H, Nairn A, Greengard P. cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones. Nature 1986, 323: 812-814. PMID: 3022154, DOI: 10.1038/323812a0.Peer-Reviewed Original ResearchConceptsIntracellular injectionCyclic GMP-dependent protein kinaseNeuronal membrane permeabilityAbsence of serotoninProtein kinaseSynaptic transmissionNeuronal functionIncrease of Ca2NeuronesCGMP-dependent protein kinaseGMP-dependent protein kinaseSerotoninSnail neuronesCyclic AMPMembrane permeabilityInjectionPhysiological roleProtein phosphorylationCa2CGMPKinaseIntracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex
Woody C, Bartfai T, Gruen E, Nairn A. Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex. Brain Research 1986, 386: 379-385. PMID: 3779415, DOI: 10.1016/0006-8993(86)90175-7.Peer-Reviewed Original ResearchConceptsMammalian motor cortexMotor cortexInput resistanceSame cortical areaCyclic GMP-dependent protein kinasePrecruciate cortexIntracellular injectionAwake catsCortical areasMicroM cGMPNeuronsCortexInjectionCGMPGMP-dependent protein kinaseProtein kinase resultsAcetylcholineProtein kinasePresent results