Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
Pardo M, Gregorio S, Montalban E, Pujadas L, Elias-Tersa A, Masachs N, Vílchez-Acosta A, Parent A, Auladell C, Girault J, Vila M, Nairn A, Manso Y, Soriano E. Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders. Frontiers In Cellular Neuroscience 2023, 17: 1143319. PMID: 37153634, PMCID: PMC10157100, DOI: 10.3389/fncel.2023.1143319.Peer-Reviewed Original ResearchOverexpression of ReelinReelin levelsNeuropsychiatric disordersExtracellular matrix protein ReelinReelin expression levelsNigrostriatal dopaminergic projectionMedium spiny neuronsFunction mouse modelsHuman psychiatric disordersStriatal parvalbuminStriatal interneuronsStriatal patchesStriatal complexSpiny neuronsDopaminergic projectionsNeuronal compositionMouse modelProtein ReelinImmunohistochemical techniquesPsychiatric disordersBipolar disorderMice exhibitStriatal structuresAdult plasticityBrain development