2016
A Comparison of the Roche Cobas HPV Test With the Hybrid Capture 2 Test for the Detection of High-Risk Human Papillomavirus Genotypes
Levi AW, Bernstein JI, Hui P, Duch K, Schofield K, Chhieng DC. A Comparison of the Roche Cobas HPV Test With the Hybrid Capture 2 Test for the Detection of High-Risk Human Papillomavirus Genotypes. Archives Of Pathology & Laboratory Medicine 2016, 140: 153-7. PMID: 26910220, DOI: 10.5858/arpa.2015-0027-oa.Peer-Reviewed Original ResearchConceptsHigh-risk human papillomavirusHuman papillomavirus assaysCobas human papillomavirus (HPV) testHigh-risk human papillomavirus DNAHybrid Capture 2 testHuman papillomavirus testingHuman papillomavirus testHuman papillomavirus DNAHuman papillomavirusPapillomavirus DNAHigh-risk human papillomavirus genotypesRoche cobas HPV testRoche CobasSurePath preparationsThinPrep specimensDiscordant resultsHybrid captureCobas HPV TestHuman papillomavirus resultsLiquid-based cytology samplesHybrid Capture 2Human papillomavirus genotypesLiquid-based preparationsHPV testCapture 2
2015
Detection and Genotype of High-Risk Human Papillomavirus in Fine-Needle Aspirates of Patients With Metastatic Squamous Cell Carcinoma Is Helpful in Determining Tumor Origin
Baldassarri R, Aronberg R, Levi AW, Yarbrough WG, Kowalski D, Chhieng D. Detection and Genotype of High-Risk Human Papillomavirus in Fine-Needle Aspirates of Patients With Metastatic Squamous Cell Carcinoma Is Helpful in Determining Tumor Origin. American Journal Of Clinical Pathology 2015, 143: 694-700. PMID: 25873503, DOI: 10.1309/ajcpcza4pszcfhq4.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCobas 4800 systemRoche cobas 4800 systemMetastatic squamous cell carcinomaFine needle aspiratesHuman papillomavirusHR-HPVCell carcinomaHPV 16High-risk (HR) HPVSquamous cell carcinoma originatingHigh-risk human papillomavirusNeck squamous cell carcinomaHPV 16/18 genotypesHR-HPV testingHR-HPV detectionHR-HPV resultsCorresponding histologic specimensLeft parapharyngeal massElectronic health recordsCarcinoma originatingMediastinal lymphadenopathyNegative HNSCCProspective studyHistologic material
2014
Detection and Genotype of High Risk Human Papillomavirus in Fine Needle Aspirates of Patients with Metastatic Squamous Cell Carcinoma is Helpful in Determining Tumor Origin
Wong R, Aronberg R, Levi A, Yarbrough W, Kowalski D, Chhieng D. Detection and Genotype of High Risk Human Papillomavirus in Fine Needle Aspirates of Patients with Metastatic Squamous Cell Carcinoma is Helpful in Determining Tumor Origin. Journal Of The American Society Of Cytopathology 2014, 3: s49-s50. DOI: 10.1016/j.jasc.2014.09.109.Peer-Reviewed Original Research
2011
Implementation of FocalPoint GS location‐guided imaging system
Levi AW, Chhieng DC, Schofield K, Kowalski D, Harigopal M. Implementation of FocalPoint GS location‐guided imaging system. Cancer Cytopathology 2011, 120: 126-133. PMID: 22505211, DOI: 10.1002/cncy.20187.Peer-Reviewed Original ResearchConceptsASC-US casesHR-HPV positive rateLow-risk patient populationHigh-risk human papillomavirusASC-US interpretationsRoutine clinical settingPromising screening toolPap testHuman papillomavirusPapanicolaou testPatient populationBacterial vaginosisDrug AdministrationSIL ratioClinical settingScreening toolDiagnostic categoriesLaboratory information systemGynecologic cytologyPrimary screeningSignificant increaseFalse negative fractionPositive rateHigh percentageCurrent studyUse of high‐risk human papillomavirus testing in patients with low‐grade squamous intraepithelial lesions
Levi AW, Harigopal M, Hui P, Schofield K, Chhieng DC. Use of high‐risk human papillomavirus testing in patients with low‐grade squamous intraepithelial lesions. Cancer Cytopathology 2011, 119: 228-234. PMID: 21732551, DOI: 10.1002/cncy.20172.Peer-Reviewed Original ResearchConceptsLow-grade squamous intraepithelial lesionsHR-HPV testingHPV testingCIN 2Colposcopy rateHR-HPVRelative light units/cutoffCervical intraepithelial neoplasia 2High-risk human papillomavirusHR-HPV statusRLU/COIntraepithelial neoplasia 2Hybrid Capture 2Squamous intraepithelial lesionsCIN 1 lesionsLarge teaching hospitalNegative predictive valueLSIL cytologyHPV statusIntraepithelial lesionsCapture 2Human papillomavirusTeaching hospitalCytologic diagnosisSevere lesions