Featured Publications
Face‐to‐face live eye‐tracking in toddlers with autism: Feasibility and impact of familiarity and face covering
Vernetti A, Butler M, Banarjee C, Boxberger A, All K, Macari S, Chawarska K. Face‐to‐face live eye‐tracking in toddlers with autism: Feasibility and impact of familiarity and face covering. Autism Research 2023, 17: 1381-1390. PMID: 38009948, DOI: 10.1002/aur.3060.Peer-Reviewed Original ResearchAutism spectrum disorderEye-tracking methodsSocial partnersAtypical developmentSocial attentionFace interactionEye-tracking taskEye-tracking procedureGroup of toddlersImpact of familiarityNeutral affectTask completion rateUnfamiliar personDiminished attentionAffective responsesSpectrum disorderNeurodevelopmental vulnerabilityParent conditionInteractive partnersIntervention outcomesInteractive faceAutismToddlersReal-world dynamicsTaskA generalizable connectome-based marker of in-scan sustained attention in neurodiverse youth
Horien C, Greene A, Shen X, Fortes D, Brennan-Wydra E, Banarjee C, Foster R, Donthireddy V, Butler M, Powell K, Vernetti A, Mandino F, O'Connor D, Lake E, McPartland J, Volkmar F, Chun M, Chawarska K, Rosenberg M, Scheinost D, Constable R. A generalizable connectome-based marker of in-scan sustained attention in neurodiverse youth. Cerebral Cortex 2022, 33: 6320-6334. PMID: 36573438, PMCID: PMC10183743, DOI: 10.1093/cercor/bhac506.Peer-Reviewed Original ResearchConceptsAttention taskAttentional stateConnectome-based predictive modelingNeurodiverse conditionsSustained attention taskAttention network modelSample of youthNeurotypical participantsSustained attentionBrain correlatesNeurobiological correlatesAttention networkIndividual participantsSeparate samplesYouthParticipantsHead motionTaskCorrelatesAttentionAutismConfoundsNetwork modelGeneralizesHealthcare settingsHypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonates
Scheinost D, Chang J, Lacadie C, Brennan-Wydra E, Foster R, Boxberger A, Macari S, Vernetti A, Constable RT, Ment LR, Chawarska K. Hypoconnectivity between anterior insula and amygdala associates with future vulnerabilities in social development in a neurodiverse sample of neonates. Scientific Reports 2022, 12: 16230. PMID: 36171268, PMCID: PMC9517994, DOI: 10.1038/s41598-022-20617-6.Peer-Reviewed Original ResearchConceptsFirst Year InventoryAnterior insulaFunctional connectivityMaternal mental health factorsLeft anterior insulaState functional connectivityMental health factorsSubsample of participantsPostmenstrual ageSalience networkFamily historySocial domainsNeural circuitryAutismSocial behaviorBrain imagingHigher likelihoodInsulaSocial developmentHypoconnectivityExploratory analysisThird trimesterFuture onsetHealth factorsRisk scoreAtypical Emotional Electrodermal Activity in Toddlers with Autism Spectrum Disorder
Vernetti A, Shic F, Boccanfuso L, Macari S, Kane‐Grade F, Milgramm A, Hilton E, Heymann P, Goodwin MS, Chawarska K. Atypical Emotional Electrodermal Activity in Toddlers with Autism Spectrum Disorder. Autism Research 2020, 13: 1476-1488. PMID: 32896980, PMCID: PMC10081486, DOI: 10.1002/aur.2374.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderPhysiological arousalTypical developmentEmotional challengesAge-matched toddlersAutism symptom severityEmotion-eliciting conditionsCore ASD symptomsSeverity of autismSkin conductance levelFear emotionCognitive processesFear conditionTD peersASD groupEmotional expressivityEmotional expressionASD symptomsPleasant eventsExternalizing problemsSpectrum disorderThreatening eventsUnderstanding of precursorsBehavioral problemsBehavioral expressionInfant neural sensitivity to eye gaze depends on early experience of gaze communication
Vernetti A, Ganea N, Tucker L, Charman T, Johnson MH, Senju A. Infant neural sensitivity to eye gaze depends on early experience of gaze communication. Developmental Cognitive Neuroscience 2018, 34: 1-6. PMID: 29890461, PMCID: PMC6252267, DOI: 10.1016/j.dcn.2018.05.007.Peer-Reviewed Original ResearchConceptsEvent-related potentialsGaze shiftsBrain responsesGaze communicationDynamic gaze shiftsInfant neural sensitivitySelective brain responsesFunctional brain developmentEye-gaze communicationBlind parentsNeural sensitivitySighted infantsEye gazeSighted parentsCommunicative experiencesPrimary caregiversHuman brainDistinct experiencesCommunication experiencesIndividual environmentsCurrent studyBrain developmentParentsEarly experienceFunctional specialisation
2024
Family history of psychiatric conditions and development of siblings of children with autism
Bellia G, Chang J, Liew Z, Vernetti A, Macari S, Powell K, Chawarska K. Family history of psychiatric conditions and development of siblings of children with autism. Autism Research 2024, 17: 1665-1676. PMID: 38896553, PMCID: PMC11341253, DOI: 10.1002/aur.3175.Peer-Reviewed Original ResearchSiblings of childrenNeuropsychiatric disordersFamilies of childrenFamily history of schizophreniaYounger siblings of childrenHistory of psychiatric conditionsHistory of schizophreniaYounger siblingsAssess autism symptomsNonverbal IQAutism symptomsBipolar disorderIntellectual disabilityPsychiatric conditionsSubclinical symptomsAdaptive skillsSocial affectAdaptive functioningAutismFamily historyParent interviewsFamily factorsMultiple regression analysisDevelopmental outcomesDisorders
2022
Attention to audiovisual speech does not facilitate language acquisition in infants with familial history of autism
Chawarska K, Lewkowicz D, Feiner H, Macari S, Vernetti A. Attention to audiovisual speech does not facilitate language acquisition in infants with familial history of autism. Journal Of Child Psychology And Psychiatry 2022, 63: 1466-1476. PMID: 35244219, DOI: 10.1111/jcpp.13595.Peer-Reviewed Original ResearchConceptsExpressive language scoresLanguage outcomesAudiovisual cuesSpeaker's faceLanguage scoresLanguage acquisitionLanguage delayBetter language outcomesSiblings of childrenFamilial riskLow familial riskPoor language outcomesLow-risk infantsAudiovisual speechIntact attentionSpeech cuesHigh familial riskPromising endophenotypeASD diagnosisSpeech processingCuesHigh-risk infantsAutismASDFace
2021
Puppets facilitate attention to social cues in children with ASD
Macari S, Chen X, Brunissen L, Yhang E, Brennan‐Wydra E, Vernetti A, Volkmar F, Chang J, Chawarska K. Puppets facilitate attention to social cues in children with ASD. Autism Research 2021, 14: 1975-1985. PMID: 34350712, PMCID: PMC8434944, DOI: 10.1002/aur.2552.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderVisual attentionAutism severityTD controlsSpeaker's faceYoung childrenSocial-communicative cuesSpeakers’ preferencesHigher autism severityAttention of childrenFunction of groupASD groupSocial cuesSpectrum disorderVisual preferenceHuman speakersSocial partnersSocial interactionSpeaker identityPuppetCuesChildrenEarly characteristicsReciprocal interactionsFace
2020
Attend Less, Fear More: Elevated Distress to Social Threat in Toddlers With Autism Spectrum Disorder
Macari SL, Vernetti A, Chawarska K. Attend Less, Fear More: Elevated Distress to Social Threat in Toddlers With Autism Spectrum Disorder. Autism Research 2020, 14: 1025-1036. PMID: 33283976, PMCID: PMC7772932, DOI: 10.1002/aur.2448.Peer-Reviewed Original ResearchConceptsAutism symptom severitySocial threatEmotional reactivityNegative emotional responsesER strategiesAmbiguous threatThreat valueEmotional responsesSocial situationsAutism Diagnostic Observation Schedule-2Potential social threatEmotion regulation strategiesER strategy useDifferential emotional reactivitySymptom severityMechanisms of changeIntensity of distressNonsocial stimuliNonsocial threatAttentional salienceTD toddlersEmotional salienceAutism phenotypeAutism severityRegulation strategies
2018
Development of Adaptive Communication Skills in Infants of Blind Parents
Ganea N, Hudry K, Vernetti A, Tucker L, Charman T, Johnson MH, Senju A. Development of Adaptive Communication Skills in Infants of Blind Parents. Developmental Psychology 2018, 54: 2265-2273. PMID: 30335435, PMCID: PMC6254470, DOI: 10.1037/dev0000564.Peer-Reviewed Original ResearchEmotional Expressivity in Toddlers With Autism Spectrum Disorder
Macari S, DiNicola L, Kane-Grade F, Prince E, Vernetti A, Powell K, Fontenelle S, Chawarska K. Emotional Expressivity in Toddlers With Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: 828-836.e2. PMID: 30392624, PMCID: PMC6844292, DOI: 10.1016/j.jaac.2018.07.872.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAutism Diagnostic Observation Schedule-2Emotional expressivenessEarly Childhood Behavior QuestionnaireAutism severityPositive emotionsSpectrum disorderGreater autism severityNegative emotional expressivenessParent-reported temperamentImportance of emotionsIntensity of fearChildhood Behavior QuestionnaireASD displayASD groupEmotional expressivityAutism symptomsVocal channelNegative emotionalityTD groupTypical developmentCognitive developmentGoal blockageIntense angerIntense fear
2017
Simulating interaction: Using gaze-contingent eye-tracking to measure the reward value of social signals in toddlers with and without autism
Vernetti A, Senju A, Charman T, Johnson MH, Gliga T, Team T. Simulating interaction: Using gaze-contingent eye-tracking to measure the reward value of social signals in toddlers with and without autism. Developmental Cognitive Neuroscience 2017, 29: 21-29. PMID: 28939027, PMCID: PMC6987892, DOI: 10.1016/j.dcn.2017.08.004.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderHR-ASD groupLow-risk controlsSocial interactionDiagnosis of ASDNaturalistic social interactionsLow familial riskSocial orientingSocial motivationASD diagnosisReward valueSocial signalsSpectrum disorderSocial videosAge 3Mechanical toysFamilial riskAge 2ToddlersPersonsOrientingAutismDifficultiesRewardMotivationGaze-contingent reinforcement learning reveals incentive value of social signals in young children and adults
Vernetti A, Smith TJ, Senju A. Gaze-contingent reinforcement learning reveals incentive value of social signals in young children and adults. Proceedings Of The Royal Society B 2017, 284: 20162747. PMID: 28250186, PMCID: PMC5360925, DOI: 10.1098/rspb.2016.2747.Peer-Reviewed Original ResearchConceptsCue-reward associationsReward-predictive cuesSocial orientingVisual attentionSocial cuesReward deliveryVisual cuesIncentive valuePositive incentive valueParticipants' visual attentionReinforcement learningVisual orientingPreferential orientingSocial stimuliRewarding outcomesSocial signalsOrientingCuesPositive outcomesYoung childrenSpontaneous indicationsLearningChildrenAdultsReal life
2015
Early Social Experience Affects the Development of Eye Gaze Processing.
Senju A, Vernetti A, Ganea N, Hudry K, Tucker L, Charman T, Johnson MH. Early Social Experience Affects the Development of Eye Gaze Processing. Current Biology : CB 2015, 25: 3086-91. PMID: 26752077, PMCID: PMC4683081, DOI: 10.1016/j.cub.2015.10.019.Peer-Reviewed Original Research
2014
Belief-based action prediction in preverbal infants.
Southgate V, Vernetti A. Belief-based action prediction in preverbal infants. Cognition 2014, 130: 1-10. PMID: 24140991, PMCID: PMC3857687, DOI: 10.1016/j.cognition.2013.08.008.Peer-Reviewed Original Research
2013
Cultural background modulates how we look at other persons' gaze.
Senju A, Vernetti A, Kikuchi Y, Akechi H, Hasegawa T, Johnson MH. Cultural background modulates how we look at other persons' gaze. International Journal Of Behavioral Development 2013, 37: 131-6. PMID: 23585703, PMCID: PMC3621509, DOI: 10.1177/0165025412465360.Peer-Reviewed Original ResearchCultural modulation of face and gaze scanning in young children.
Senju A, Vernetti A, Kikuchi Y, Akechi H, Hasegawa T. Cultural modulation of face and gaze scanning in young children. PloS One 2013, 8: e74017. PMID: 23991212, PMCID: PMC3753244, DOI: 10.1371/journal.pone.0074017.Peer-Reviewed Original Research