2012
Can primary tumor markers of cancer-initiating cells predict lymph node positivity in breast cancer patients?
Chagpar A, Neumeister V, Lannin D, Rimm D. Can primary tumor markers of cancer-initiating cells predict lymph node positivity in breast cancer patients? Journal Of Clinical Oncology 2012, 30: 1121-1121. DOI: 10.1200/jco.2012.30.15_suppl.1121.Peer-Reviewed Original ResearchBreast cancer patientsLN statusCancer patientsLymphovascular invasionTumor sizeTumor markersPositive LNsPoor prognosisMedian numberPrimary tumor markersMedian patient ageMedian tumor sizeLymph node positivityLN-positive patientsLymph node statusOnly factorCancer initiating cellsCancer-initiating cellsLevels of CD44Axillary surgeryLN positivityNode positivityPatient agePositive patientsClinicopathologic data
2009
Use Pre- and Intra-Operative Data To Predict Probability of Positive Non-Sentinel Lymph Nodes.
Chagpar A, Blumencranz P, Whitworth P, Deck K, Rosenberg A, Simmons R, Reintgen D, Beitsch P, Julian T, Saha S, Mamounas E, Giuliano A, Cook E, Wang S. Use Pre- and Intra-Operative Data To Predict Probability of Positive Non-Sentinel Lymph Nodes. Cancer Research 2009, 69: 302-302. DOI: 10.1158/0008-5472.sabcs-09-302.Peer-Reviewed Original ResearchAxillary node dissectionNon-SLN metastasisTumor sizeIntra-operative dataBLN AssayPositive SLNMedian numberLogistic regression modelsPositive non-sentinel lymph nodesSentinel lymph node-positive patientsCompletion axillary node dissectionFrozen sectionsLymph node-positive patientsNon-sentinel lymph nodesStepwise logistic regression modelFurther positive nodesNon-SLN statusMedian tumor sizeNode-positive patientsPositive rateTumor size dataSignificant predictorsCohort of interestNode dissectionPositive nodesUse of intraoperative breast cancer sentinel lymph node (SLN) assay to predict of ≥4 positive (+) lymph nodes (LN)
Chagpar A, Blumencranz P, Whitworth P, Deck K, Rosenberg A, Simmons R, Reintgen D, Beitsch P, Saha S, Julian T. Use of intraoperative breast cancer sentinel lymph node (SLN) assay to predict of ≥4 positive (+) lymph nodes (LN). Journal Of Clinical Oncology 2009, 27: 530-530. DOI: 10.1200/jco.2009.27.15_suppl.530.Peer-Reviewed Original ResearchSentinel lymph nodesLymph nodesFinal pathologyTumor sizeMedian cycle timeBreast cancer sentinel lymph nodesTotal lymph nodesMedian tumor sizePositive lymph nodesImmediate breast reconstructionHematoxylin-eosin stainingReceiver operator curveCohort of interestBLN AssayQuantitative RT-PCRSLN metastasisProspective studyBreast reconstructionReal-time RT-PCR analysisMedian numberClinical utilityRadiation therapyPatientsMultivariate analysisMammaglobin