2023
Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea
Baldassarri S, Chu J, Deng A, Xu Z, Blohowiak R, Byrne S, Kushida C, Yaggi H, Zinchuk A. Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea. Sleep And Breathing 2023, 27: 2479-2490. PMID: 37058215, PMCID: PMC10576010, DOI: 10.1007/s11325-023-02830-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultCaffeineCross-Sectional StudiesEthanolFemaleHumansMaleMiddle AgedNicotineSleep Apnea, ObstructiveSubstance-Related DisordersConceptsUntreated obstructive sleep apneaObstructive sleep apneaApnea Positive Pressure Long-term Efficacy StudySubstance useDaytime symptomsSleep characteristicsSleep durationCaffeine useModerate caffeine useLong-term Efficacy StudyCurrent cigarette smokersHeavy caffeine usersObjective sleep characteristicsShort sleep durationModerate alcohol useMore REM sleepLower sleep durationHeavy alcohol usersCross-sectional analysisPsychoactive substance useCurrent smokersCurrent smokingComorbid conditionsMedian BMISleep apneaPeriodic limb movements during sleep and risk of hypertension: A systematic review
Srivali N, Thongprayoon C, Tangpanithandee S, Krisanapan P, Mao M, Zinchuk A, Koo B, Cheungpasitporn W. Periodic limb movements during sleep and risk of hypertension: A systematic review. Sleep Medicine 2023, 102: 173-179. PMID: 36701831, PMCID: PMC10388290, DOI: 10.1016/j.sleep.2023.01.008.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesHumansHypertensionNocturnal Myoclonus SyndromePolysomnographyProspective StudiesSleepConceptsPooled risk ratioPeriodic limb movementsRisk of hypertensionRisk ratioSystematic reviewGeneric inverse variance methodEgger's regression asymmetry testLimb movementsStandardized incidence ratiosConfidence intervalsInverse variance methodHazard ratioIncidence ratiosHypertension riskInterventional studyEligible studiesOdds ratioRelative riskObservational studyStatistical heterogeneityFunnel plotHypertensionPLMSPublication biasRelevant articles
2018
Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea.
Zinchuk A, Edwards BA, Jeon S, Koo BB, Concato J, Sands S, Wellman A, Yaggi HK. Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea. Journal Of Clinical Sleep Medicine 2018, 14: 809-817. PMID: 29734986, PMCID: PMC5940432, DOI: 10.5664/jcsm.7112.Peer-Reviewed Original ResearchConceptsLong-term CPAP useObstructive sleep apneaLow respiratory arousal thresholdLow ArTHRespiratory arousal thresholdCPAP useNonobese patientsClinical featuresSleep apneaOdds ratioArousal thresholdContinuous positive airway pressure usePositive airway pressure usePhysiologic phenotypeRegular CPAP useAntihypertensive medication useBody mass indexAssociated clinical featuresUnited States veteransAntihypertensive medicationsPolysomnography characteristicsClinical characteristicsCPAP adherenceAntidepressant useMedication use
2017
Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea
Zinchuk AV, Jeon S, Koo BB, Yan X, Bravata DM, Qin L, Selim BJ, Strohl KP, Redeker NS, Concato J, Yaggi HK. Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea. Thorax 2017, 73: 472. PMID: 28935698, PMCID: PMC6693344, DOI: 10.1136/thoraxjnl-2017-210431.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedCardiovascular DiseasesCluster AnalysisCross-Sectional StudiesFemaleHumansIschemic Attack, TransientLongitudinal StudiesMaleMiddle AgedMortalityPhenotypePolysomnographyProportional Hazards ModelsRisk AssessmentSeverity of Illness IndexSleep Apnea, ObstructiveStrokeConceptsObstructive sleep apnoeaCardiovascular outcomesPolysomnographic featuresSleep apnoeaPolysomnographic dataIncident transient ischemic attackUS Veteran cohortTransient ischemic attackAcute coronary syndromeAdverse cardiovascular outcomesPeriodic limb movementsOSA severity classificationPolysomnographic phenotypeCoronary syndromeIschemic attackCardiovascular implicationsOSA phenotypesOSA evaluationPathophysiological domainsPoor sleepMild/Patient clustersVeteran cohortSurvival analysisCombined outcome
2016
The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.
Selim BJ, Koo BB, Qin L, Jeon S, Won C, Redeker NS, Lampert RJ, Concato JP, Bravata DM, Ferguson J, Strohl K, Bennett A, Zinchuk A, Yaggi HK. The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study. Journal Of Clinical Sleep Medicine 2016, 12: 829-37. PMID: 26951420, PMCID: PMC4877315, DOI: 10.5664/jcsm.5880.Peer-Reviewed Original ResearchConceptsSleep-disordered breathingNocturnal cardiac arrhythmiasIntraventricular conduction delayApnea-hypopnea indexCardiac arrhythmiasTwo-fold oddsModerate-severe sleep-disordered breathingSeverity of SDBSevere sleep-disordered breathingComplex ventricular ectopyMultiple cardiovascular comorbiditiesObstructive respiratory eventsClinic-based populationCross-sectional analysisCardiovascular comorbiditiesSDB patientsVentricular ectopySDB severityRespiratory eventsUnadjusted oddsSupraventricular tachycardiaCardiovascular diseaseArrhythmia subtypesArrhythmia riskConduction delay