2024
Arousal threshold modifies the effect of CPAP on executive function among individuals with obstructive sleep apnea.
Zinchuk A, Kushida C, Walker A, Wellman A, Azarbarzin A, Alex R, Varga A, Sands S, Yaggi H. Arousal threshold modifies the effect of CPAP on executive function among individuals with obstructive sleep apnea. European Respiratory Journal 2024, 2401183. PMID: 39572221, DOI: 10.1183/13993003.01183-2024.Peer-Reviewed Original ResearchEffect of continuous positive airway pressureContinuous positive airway pressureObstructive sleep apneaSleep apneaArousal thresholdApnea Positive Pressure Long-term Efficacy StudySham continuous positive airway pressureEffect of CPAP treatmentPositive airway pressureLong-term efficacy studiesAssociated with neurocognitive dysfunctionCPAP treatmentAirway pressureSham-controlled trialApneaRandomized trialsSecondary outcomesNeurocognitive dysfunctionNeurocognitive outcomesTotal timeEfficacy studiesNeurocognitive functionSecondary analysisArTHExecutive function
2023
0522 CPAP Improves Cognition in Brain-Healthy Males: Secondary Analysis of a Randomized Trial
Sun H, Zinchuk A, Locascio J, Kushida C, Thomas R, Westover M. 0522 CPAP Improves Cognition in Brain-Healthy Males: Secondary Analysis of a Randomized Trial. Sleep 2023, 46: a230-a231. DOI: 10.1093/sleep/zsad077.0522.Peer-Reviewed Original ResearchObstructive sleep apneaApnea Positive Pressure Long-term Efficacy StudyPrimary analysisIndividual treatment effectsIntroduction Obstructive sleep apneaSecondary analysisLong-term Efficacy StudyBaseline cognitive scoresBrain age indexBaseline AHIBaseline polysomnogramMulticenter trialRandomized trialsSleep apneaAdherence ratesOSA treatmentTwo-armGroup 2Group 1Efficacy studiesCognitive impairmentCPAPBaseline cognitionMore depressionCognitive scores