Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness.
Azarbarzin A, Zinchuk A, Wellman A, Labarca G, Vena D, Gell L, Messineo L, White DP, Gottlieb DJ, Redline S, Peker Y, Sands SA. Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 767-774. PMID: 35579605, PMCID: PMC9799106, DOI: 10.1164/rccm.202111-2608oc.Peer-Reviewed Original ResearchConceptsContinuous positive airway pressureObstructive sleep apneaAdverse cardiovascular outcomesPositive airway pressureCardiovascular outcomesAirway pressureCardiovascular benefitsCardiovascular riskSleep apneaExcessive sleepinessEffect of CPAPMultivariable Cox regressionProspective clinical trialsCoronary artery diseaseGreater cardiovascular benefitPulse rate responsesSignificant risk reductionCPAP therapyRepeat revascularizationBaseline polysomnographyCardiovascular mortalityArtery diseasePrimary outcomeCox regressionRespiratory events