Linking the epigenetic ‘language’ of covalent histone modifications to cancer
Hake SB, Xiao A, Allis CD. Linking the epigenetic ‘language’ of covalent histone modifications to cancer. British Journal Of Cancer 2004, 90: 761-769. PMID: 14970850, PMCID: PMC2410168, DOI: 10.1038/sj.bjc.6601575.Peer-Reviewed Original ResearchMeSH KeywordsAcetylationCell Transformation, NeoplasticChromatin Assembly and DisassemblyDNA MethylationGene Expression Regulation, NeoplasticHistonesHumansNeoplasmsPhosphorylationConceptsCovalent histone modificationsHistone modificationsMethylation of DNAChromatin reorganisationEpigenetic modulationCovalent modificationHuman biologyHuman cancersMultistep processMethylationRecent findingsChromatinHuman healthHistonesEpigeneticsPhosphorylationBiologyAcetylationDNAModificationPotential therapyCarcinogenesisMajor partCancer