Arginine Methylation of Runx1 Regulates Its Biological and Transcriptional Activities.
Zhao X, Parkanani A, Zhang J, Dunne R, Xiao A, Allis C, Nimer S. Arginine Methylation of Runx1 Regulates Its Biological and Transcriptional Activities. Blood 2004, 104: 2041. DOI: 10.1182/blood.v104.11.2041.2041.Peer-Reviewed Original ResearchArginine methylation sitesProtein arginine methyltransferasesArginine methylationRunt domainMethylation sitesTranscriptional repression complexAbility of RUNX1Co-immunoprecipitation assaysChromatin immunoprecipitation assaysSite-specific mutagenesisCell proliferation signalsCarboxy-terminal regionLuciferase gene reporterRepression complexDefinitive hematopoiesisArginine methyltransferasesTranscriptional activatingGATA-1Repressor proteinLysine acetylationMass spectrometry analysisTranscription factorsImmunoprecipitation assaysSerine phosphorylationGene transcription