Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury
Li L, Black R, Ma Z, Yang Q, Wang A, Lin F. Use of mouse hematopoietic stem and progenitor cells to treat acute kidney injury. American Journal Of Physiology. Renal Physiology 2011, 302: f9-f19. PMID: 21937606, PMCID: PMC3251347, DOI: 10.1152/ajprenal.00377.2011.Peer-Reviewed Original ResearchConceptsAcute kidney injuryKidney injuryMouse hematopoietic stemProgenitor cellsHematopoietic stemEpithelial marker E-cadherinRenal ischemic injuryTubular cell deathCell fate conversionMarker E-cadherinEmbryonic kidney organ cultureHistone deacetylase inhibitorsKidney organ culturesIschemic injuryKidney functionPostischemic kidneyTubular repairRenal capsuleRenal repairRenotrophic factorIGF-1Intravenous injectionEffective treatmentFate conversionEpithelial proliferation