2023
CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection
Prendergast A, Jim K, Marnas H, Desban L, Quan F, Djenoune L, Laghi V, Hocquemiller A, Lunsford E, Roussel J, Keiser L, Lejeune F, Dhanasekar M, Bardet P, Levraud J, van de Beek D, Vandenbroucke-Grauls C, Wyart C. CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current Biology 2023, 33: 940-956.e10. PMID: 36791723, DOI: 10.1016/j.cub.2023.01.039.Peer-Reviewed Original ResearchConceptsCentral nervous systemCerebrospinal fluidSensory neuronsNervous systemStreptococcus pneumoniaeCentral nervous system infectionBlockade of neurotransmissionCentral sensory neuronsNervous system infectionHost survivalPeripheral nervous systemCell-specific ablationEpileptic-like seizuresCSF-contacting neuronsSupernatants of cellsPneumococcal meningitisSystem infectionBitter taste receptorsCSF infectionPneumoniae infectionNeurotropic virusesSpinal cordPathogenic bacteriaPostural controlMeningitis
2014
Chapter 13 Neural Crest Cells and Peripheral Nervous System Development
Prendergast A, Raible D. Chapter 13 Neural Crest Cells and Peripheral Nervous System Development. 2014, 255-286. DOI: 10.1016/b978-0-12-401730-6.00014-4.Peer-Reviewed Original ResearchTrunk neural crestNeural crestDorsal root gangliaPeripheral nervous systemTranscription factor cascadeCell fate decisionsMultipotent cell populationPeripheral nervous system developmentGene regulatory networksNeural crest cellsNervous system developmentFate decisionsRegulatory networksTranscription factorsCrest cellsCell typesNeuronal subtypesSympathetic chain gangliaSequential cascadeCell populationsChain gangliaRoot gangliaTrk receptorsSympathetic neuronsExpression