2009
An fMRI Study of the Effects of Psychostimulants on Default-Mode Processing During Stroop Task Performance in Youths With ADHD
Peterson BS, Potenza MN, Wang Z, Zhu H, Martin A, Marsh R, Plessen KJ, Yu S. An fMRI Study of the Effects of Psychostimulants on Default-Mode Processing During Stroop Task Performance in Youths With ADHD. American Journal Of Psychiatry 2009, 166: 1286-1294. PMID: 19755575, PMCID: PMC3289412, DOI: 10.1176/appi.ajp.2009.08050724.Peer-Reviewed Original ResearchConceptsVentral anterior cingulate cortexAnterior cingulate cortexEffects of psychostimulantsCingulate cortexComparison subjectsLateral prefrontal cortexPrefrontal cortexStimulant medicationDefault-mode activityFunctional MRI scansPosterior cingulate cortexVentral anterior cingulateDefault mode processingMedicationsMRI scansAnterior cingulateHealthy comparison youthNormal levelsCortexPsychostimulantsGreater activationFMRI studyGreater reductionLateral prefrontalBrain activity
2003
Frontostriatal Abnormalities in Adolescents With Bipolar Disorder: Preliminary Observations From Functional MRI
Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, Fulbright RK, Gore JC, Charney DS, Krystal JH, Peterson BS. Frontostriatal Abnormalities in Adolescents With Bipolar Disorder: Preliminary Observations From Functional MRI. American Journal Of Psychiatry 2003, 160: 1345-1347. PMID: 12832254, DOI: 10.1176/appi.ajp.160.7.1345.Peer-Reviewed Original ResearchConceptsBipolar disorder groupBipolar disorderHealthy groupComparison subjectsDisorder groupNormal comparison subjectsAdult bipolar disorderHealthy comparison subjectsPresence of dysfunctionFunctional magnetic resonance imagingMagnetic resonance imagingBipolar disorder subjectsAge-related increaseEvent-related functional magnetic resonance imagingFrontostriatal abnormalitiesLeft putamenFunctional abnormalitiesPrefrontal abnormalitiesDepressive symptomsResonance imagingVentral striatumFrontostriatal circuitsDisorder subjectsFunctional MRIDevelopmental disturbances