2024
Self-stigma mediates the relationships between childhood maltreatment and symptom levels of PTSD, depression, and anxiety
Haim-Nachum S, Lazarov A, Zabag R, Martin A, Bergman M, Neria Y, Amsalem D. Self-stigma mediates the relationships between childhood maltreatment and symptom levels of PTSD, depression, and anxiety. European Journal Of Psychotraumatology 2024, 15: 2370174. PMID: 38985020, PMCID: PMC11238652, DOI: 10.1080/20008066.2024.2370174.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderChildhood maltreatmentSelf-stigmaChildhood abuseSymptom severity of depressionSymptom typeSubtypes of childhood maltreatmentSurvivors of childhood abuseChildhood trauma survivorsSeverity of depressionChildhood maltreatment experiencesSymptoms of depressionEffects of self-stigmaInternalization of negative stereotypesIncreased self-stigmaMental health problemsSignificant mediation effectAnxiety symptomsStress disorderChildhood neglectSymptom levelsMaltreatment experiencesTrauma survivorsSymptom severityPhysical neglect
2023
Stigma Reduction Via Brief Video Interventions: Comparing Presentations by an Actor Versus a Person With Lived Experience
Amsalem D, Jankowski S, Pagdon S, Markowitz J, Martin A, Dixon L. Stigma Reduction Via Brief Video Interventions: Comparing Presentations by an Actor Versus a Person With Lived Experience. Psychiatric Services 2023, 75: 485-488. PMID: 38088037, DOI: 10.1176/appi.ps.20230215.Peer-Reviewed Original ResearchConceptsIntervention groupMental illnessReduce mental health-related stigmaMental health-related stigmaExperience of mental illnessHealth-related stigmaDomains of stigmaFocus groups of individualsStigma scoresPersonal recoveryVideo interventionFocus groupsStigmaInterventionLived experienceGroup of individualsFollow-upIllnessControl groupPersonal storiesPostinterventionComparative presentationPersonsNoninferiority analysisGroup
2021
Review: Ecological awareness, anxiety, and actions among youth and their parents – a qualitative study of newspaper narratives
Benoit L, Thomas I, Martin A. Review: Ecological awareness, anxiety, and actions among youth and their parents – a qualitative study of newspaper narratives. Child And Adolescent Mental Health 2021, 27: 47-58. PMID: 34687125, DOI: 10.1111/camh.12514.Peer-Reviewed Original ResearchConceptsClimate crisisYoung peopleYouth-led activismClimate change anxietyPatterns of discourseYoung activistsClimate changePress narrativesDiscourse analysisClimate actionImmature waysUltimate saviourYouth concernsSources of meaningNewspaper articlesNewspaper narrativesAttitudes of childrenInnocent victimsParadigmatic wayQualitative studyNVivo softwareEnvironmental actionsRespective perspectivesAmerican newspapersDefensive stance
2020
Narrative Matters: Adult anxieties and prejudice against children – childism in The Twilight Zone
Thomas I, Martin A. Narrative Matters: Adult anxieties and prejudice against children – childism in The Twilight Zone. Child And Adolescent Mental Health 2020, 26: 89-91. PMID: 32970900, PMCID: PMC7855219, DOI: 10.1111/camh.12423.Commentaries, Editorials and LettersThe Mental Status Exam: An Online Teaching Exercise Using Video-Based Depictions by Simulated Patients
Martin A, Jacobs A, Krause R, Amsalem D. The Mental Status Exam: An Online Teaching Exercise Using Video-Based Depictions by Simulated Patients. MedEdPORTAL 2020, 16: 10947. PMID: 32875093, PMCID: PMC7450674, DOI: 10.15766/mep_2374-8265.10947.Peer-Reviewed Original ResearchConceptsMental status examUndergraduate medical educationObsessive-compulsive disorderPhysical examClinical dataPsychiatric signsBipolar disorderScoring toolPatientsEntrustable professional activitiesSimulated patientsClinical psychiatryVideo clipsExerciseDisordersIncremental numberExamMedical educationExperienced learnersOnline exercisesTeaching exerciseProfessional activityVolunteer studentsEducational complementShort video clipsReducing Stigma Toward Psychiatry Among Medical Students: A Multicenter Controlled Trial.
Amsalem D, Gothelf D, Dorman A, Goren Y, Tene O, Shelef A, Horowitz I, Dunsky LL, Rogev E, Klein EH, Mekori-Domachevsky E, Fischel T, Levkovitz Y, Martin A, Gross R. Reducing Stigma Toward Psychiatry Among Medical Students: A Multicenter Controlled Trial. The Primary Care Companion For CNS Disorders 2020, 22 PMID: 32135042, DOI: 10.4088/pcc.19m02527.Peer-Reviewed Original Research
2019
Attitudes to psychiatry and to mental illness among nursing students: Adaptation and use of two validated instruments in preclinical education
Martin A, Krause R, Chilton J, Jacobs A, Amsalem D. Attitudes to psychiatry and to mental illness among nursing students: Adaptation and use of two validated instruments in preclinical education. Journal Of Psychiatric And Mental Health Nursing 2019, 27: 308-317. PMID: 31789466, PMCID: PMC8904187, DOI: 10.1111/jpm.12580.Peer-Reviewed Original ResearchConceptsSerious mental illnessMental health nursingMental illnessHealth nursingHealthcare providersPatient careInternalized stigmaTime pointsNursing studentsHealth-seeking behaviourSelf-Compassion Scale-Short FormHistory of diagnosisOMS-HCNursing schoolsResults SeventyFellow nursesPsychiatric carePAPER ADDSStigmatized viewsATP-30Help-seeking behaviorIllnessScale-Short FormFirst-year nursing studentsNursesThe Mental Status Exam Through Video Clips of Simulated Psychiatric Patients: an Online Educational Resource
Martin A, Krause R, Jacobs A, Chilton J, Amsalem D. The Mental Status Exam Through Video Clips of Simulated Psychiatric Patients: an Online Educational Resource. Academic Psychiatry 2019, 44: 179-183. PMID: 31858445, PMCID: PMC7082206, DOI: 10.1007/s40596-019-01140-9.Peer-Reviewed Original ResearchConceptsOnline educational resourcesOnline video repositoryAvailable online repositoryMental status examCurricular initiativesEducational resourcesTeaching effortsDidactic efficacyPsychiatric educatorsVideo clipsPsychiatry courseMedical studentsPsychiatric educationOverall scoreStudentsEducation trialInnovative waysExamIntervention groupVideo repositoriesMethodsThe authorsOnline repositoryEducatorsLearnersEducationChild and Adolescent Psychiatry Perceptions and Career Preference: Participation in a National Medical Student Conference Improves Outcomes
Kishore A, Sun K, Guth S, Kolevzon A, Martin A. Child and Adolescent Psychiatry Perceptions and Career Preference: Participation in a National Medical Student Conference Improves Outcomes. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 3-7. PMID: 31585159, DOI: 10.1016/j.jaac.2019.07.949.Peer-Reviewed Original Research
2012
ADHD medication use following FDA risk warnings.
Barry CL, Martin A, Busch SH. ADHD medication use following FDA risk warnings. The Journal Of Mental Health Policy And Economics 2012, 15: 119-25. PMID: 23001280, PMCID: PMC3896970.Peer-Reviewed Original Research
2006
Parent satisfaction in a multi-site acute trial of risperidone in children with autism: a social validity study
Tierney E, Aman M, Stout D, Pappas K, Arnold LE, Vitiello B, Scahill L, McDougle C, McCracken J, Wheeler C, Martin A, Posey D, Shah B. Parent satisfaction in a multi-site acute trial of risperidone in children with autism: a social validity study. Psychopharmacology 2006, 191: 149-157. PMID: 17123125, DOI: 10.1007/s00213-006-0604-z.Peer-Reviewed Original ResearchConceptsClinical trialsClinical trial proceduresParent satisfactionDouble-blind clinical trialRandomized clinical trialsTrial proceduresResearch participationClinical responseAcute trialTreatment outcomesActive drugSimilar childrenStudy proceduresTrialsPharmacological researchAutistic disorderLearning TestPlaceboChildren's research participationEthnic minority subjectsChildrenRisperidoneWhite participantsGood allianceDrugsAge, Rapid-Cycling, and Pharmacotherapy Effects on Ventral Prefrontal Cortex in Bipolar Disorder: A Cross-Sectional Study
Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS. Age, Rapid-Cycling, and Pharmacotherapy Effects on Ventral Prefrontal Cortex in Bipolar Disorder: A Cross-Sectional Study. Biological Psychiatry 2006, 59: 611-618. PMID: 16414030, DOI: 10.1016/j.biopsych.2005.08.031.Peer-Reviewed Original ResearchConceptsHealthy comparison subjectsWhite matter volumeMagnetic resonance imagingMatter volumeBD patientsHigh-resolution structural magnetic resonance imagingYoung adulthoodStructural magnetic resonance imagingTotal brain volumeCross-sectional studyGray matter volumeAge group interactionVentral prefrontal cortexPharmacotherapy effectsPrefrontal cortex functionIllness featuresBD IProtective effectVolume abnormalitiesHC subjectsComparison subjectsBrain volumeVolume deficitsBipolar disorderRapid initial declineSelective Serotonin Reuptake Inhibitors and Suicidality in Juveniles: Review of the Evidence and Implications for Clinical Practice
Rey JM, Martin A. Selective Serotonin Reuptake Inhibitors and Suicidality in Juveniles: Review of the Evidence and Implications for Clinical Practice. Child And Adolescent Psychiatric Clinics Of North America 2006, 15: 221-237. PMID: 16321732, DOI: 10.1016/j.chc.2005.08.012.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsSerotonin reuptake inhibitorsReuptake inhibitorsClinical practiceCareful clinical monitoringPharmacologic treatmentMedication complianceManic switchingSevere depressionClinical monitoringSuicidal behaviorBehavioral activationSuicidalityPersonal sufferingDepressionInhibitorsEvidenceNontreatment
2005
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders 2005, 7: 570-576. PMID: 16403182, PMCID: PMC2291299, DOI: 10.1111/j.1399-5618.2005.00264.x.Peer-Reviewed Original ResearchConceptsAmygdala volumeBipolar disorderYoung adultsAmygdala volume abnormalitiesTotal brain volumeHigh-resolution magnetic resonancePreliminary evidenceSubjects longitudinal designPersistent abnormalitiesMixed-model statistical analysisBD IVolume abnormalitiesHealthy comparison participantsBrain volumeHealthy participantsAbnormalitiesAdultsAdolescentsComparison participantsAmygdalaDevelopmental epochsDisordersLongitudinal designParticipantsMagnetic resonanceSudden death in a patient with Tourette syndrome during a clinical trial of ziprasidone
Scahill L, Blair J, Leckman JF, Martin A. Sudden death in a patient with Tourette syndrome during a clinical trial of ziprasidone. Journal Of Psychopharmacology 2005, 19: 205-206. PMID: 15728441, DOI: 10.1177/0269881105049042.Peer-Reviewed Original ResearchAntidepressant‐Induced Manic Conversion: A Developmentally Informed Synthesis of the Literature
Lim CJ, Leckman JF, Young C, Martin A. Antidepressant‐Induced Manic Conversion: A Developmentally Informed Synthesis of the Literature. International Review Of Neurobiology 2005, 65: 25-52. PMID: 16140052, DOI: 10.1016/s0074-7742(04)65002-1.Peer-Reviewed Original ResearchConceptsAddition of antidepressantsResolution of symptomsAntidepressant-induced maniaSerotonin reuptake inhibitorsMood stabilizer therapyLess nursing careMost case reportsRapid cyclingManic conversionSpontaneous maniaAntidepressant medicationReuptake inhibitorsAntidepressant exposureBipolar depressionCase reportManic episodesMood destabilizationSpontaneous episodesDistressing conditionSevere depressionClinical recommendationsManic symptomsNursing careSelective SSRIPatient screening
2004
Age Effects on Antidepressant-Induced Manic Conversion
Martin A, Young C, Leckman JF, Mukonoweshuro C, Rosenheck R, Leslie D. Age Effects on Antidepressant-Induced Manic Conversion. JAMA Pediatrics 2004, 158: 773-780. PMID: 15289250, DOI: 10.1001/archpedi.158.8.773.Peer-Reviewed Original ResearchConceptsManic conversionAntidepressant classesPatient ageTime-dependent Cox proportional hazards modelsSelective serotonin reuptake inhibitorsCox proportional hazards modelNonbipolar mood disorderSerotonin reuptake inhibitorsProportional hazards modelRisk of conversionAdministrative national databaseEffect of agePharmacy claimsReuptake inhibitorsAntidepressant exposureDrug therapyTricyclic antidepressantsPeripubertal childrenAge effectsBipolar illnessMood disordersHigh riskMental health usersAntidepressant categoryHazards model
2003
Amygdala and Hippocampal Volumes in Adolescents and Adults With Bipolar Disorder
Blumberg HP, Kaufman J, Martin A, Whiteman R, Zhang JH, Gore JC, Charney DS, Krystal JH, Peterson BS. Amygdala and Hippocampal Volumes in Adolescents and Adults With Bipolar Disorder. JAMA Psychiatry 2003, 60: 1201-1208. PMID: 14662552, DOI: 10.1001/archpsyc.60.12.1201.Peer-Reviewed Original ResearchConceptsHippocampal volumeMedial temporal lobe structuresTemporal lobe structuresBipolar disorderIllness featuresVeterans Affairs Medical CenterLobe structuresRepeated-measures statistical analysisCourse of illnessTotal brain volumeAmygdala volume reductionsBD type IAnatomic magnetic resonanceHealthy comparison subjectsPaucity of dataVolume reductionSignificant volume reductionVolumetric abnormalitiesNeurodegenerative changesIllness durationOutpatient treatmentUniversity HospitalGreater effect sizeMedical CenterHippocampal region
2002
Effects of Development on Olanzapine-Associated Adverse Events
WOODS SW, MARTIN A, SPECTOR SG, MCGLASHAN TH. Effects of Development on Olanzapine-Associated Adverse Events. Journal Of The American Academy Of Child & Adolescent Psychiatry 2002, 41: 1439-1446. PMID: 12447030, DOI: 10.1097/00004583-200212000-00015.Peer-Reviewed Original ResearchConceptsLiver function abnormalitiesAdverse eventsFunction abnormalitiesAtypical antipsychoticsComplaint riskWeight gainAtypical antipsychotic medicationsExtrapyramidal syndromeTardive dyskinesiaProlactin increaseAntipsychotic medicationAdolescent patientsRisk ratioPatient exposureSurveillance databaseAge groupsOlanzapineComplaintsConfidence intervalsExposure estimatesAntipsychoticsSedationPatientsChildrenAdults
2001
Are child-, adolescent-, and adult-onset depression one and the same disorder?
Kaufman J, Martin A, King R, Charney D. Are child-, adolescent-, and adult-onset depression one and the same disorder? Biological Psychiatry 2001, 49: 980-1001. PMID: 11430841, DOI: 10.1016/s0006-3223(01)01127-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntidepressive Agents, TricyclicAnti-Inflammatory AgentsBrainChildCorticotropin-Releasing HormoneDepressive Disorder, MajorDexamethasoneDiagnosis, DifferentialGrowth Hormone-Releasing HormoneHumansHydrocortisoneImmunity, CellularMagnetic Resonance ImagingSerotoninThyroid HormonesConceptsAdult-onset depressionBasal cortisol secretionStage of illnessSerotonergic probeTricyclic medicationDepressed cohortClinical outcomesCortisol secretionHormone infusionIllness factorsTreatment responsePreclinical studiesSame disorderDepressed adultsImmunity indicesDepression oneFamilial subtypeNeurobiological assessmentNeurobiological correlatesChildrenAdolescentsIllnessDiscrepant findingsNeuroimaging paradigmDepression