No association of posttraumatic stress disorder with epigenetic aging in women at mid-life: A longitudinal cohort study
Roberts A, Ratanatharathorn A, Chibnik L, Zhu Y, Jha S, Kang J, Wolf E, Kubzansky L, Koenen K. No association of posttraumatic stress disorder with epigenetic aging in women at mid-life: A longitudinal cohort study. Brain Behavior And Immunity 2024, 123: 672-680. PMID: 39424013, DOI: 10.1016/j.bbi.2024.10.003.Peer-Reviewed Original ResearchPosttraumatic stress disorderBody mass indexAssociation of posttraumatic stress disorderPhysical activityDiet qualityAssociated with epigenetic agingEpigenetic ageAncestry principal componentsStress disorderReference group of womenHigher body mass indexLongitudinal cohort studySelf-reported raceCo-occurring depressionDiseases of agingCross-sectional analysisMiddle-aged womenGroup of womenAssociated with mortalityDepression statusHealth factorsLongitudinal associationsMid-lifeDunedinPoAmCohort studyAssociation between childhood abuse and risk of post-COVID-19 conditions: Results from three large prospective cohort studies
Vyas C, Wang S, Menor A, Kubzansky L, Slopen N, Rich-Edwards J, Chavarro J, Kang J, Roberts A. Association between childhood abuse and risk of post-COVID-19 conditions: Results from three large prospective cohort studies. Brain Behavior And Immunity 2024, 123: 143-150. PMID: 39191351, DOI: 10.1016/j.bbi.2024.08.046.Peer-Reviewed Original ResearchPost-COVID-19 conditionPost-COVID conditionsHealth-relatedPhysical/emotional abusePsychological factorsRisk of poor health outcomesGrowing Up Today StudyNurses' Health StudyPoor health outcomesAssociated with riskAssociated with increased riskChildhood abusePost-COVID-19COVID-19 surveyCOVID-19 questionnaireHealth outcomesHealth StudyProspective studyEmotional abuse subscaleSexual abuseSelf-reportCohort studyNo childhood abuseCOVID-19-related symptomsToday StudyPost-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women – CORRIGENDUM
Liu J, Roberts A, Lawn R, Jha S, Sampson L, Sumner J, Kang J, Rimm E, Grodstein F, Liang L, Haneuse S, Kubzansky L, Koenen K, Chibnik L. Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women – CORRIGENDUM. Psychological Medicine 2024, 54: 2312-2312. PMID: 38801090, DOI: 10.1017/s0033291724001107.Peer-Reviewed Original ResearchPrepandemic Resilience to Trauma and COVID-19 Infection in Older Women
Scoglio A, Choi K, Nishimi K, Sampson L, Koenen K, Roberts A, Jha S, Kubzansky L. Prepandemic Resilience to Trauma and COVID-19 Infection in Older Women. Psychosomatic Medicine 2024, 86: 625-632. PMID: 38573019, PMCID: PMC11371542, DOI: 10.1097/psy.0000000000001304.Peer-Reviewed Original ResearchPsychological resilienceSelf-reportLifetime trauma exposureAssociated with lower riskLow psychological resilienceTrauma exposureCOVID-19-related risk factorsLifetime traumaPsychosocial interventionsNurses' Health Study IIPsychological healthPsychological assetsImprove health outcomesLow riskPhysical healthResilience scoresProtective factorsStudy IIPositive COVID-19 test resultSymptomsCOVID-19 test resultsHealth outcomesCohort participantsCOVID-19 infectionSocio-demographicMultigenerational association between smoking and autism spectrum disorder: findings from a nationwide prospective cohort study
Yim G, Roberts A, Lyall K, Ascherio A, Weisskopf M. Multigenerational association between smoking and autism spectrum disorder: findings from a nationwide prospective cohort study. American Journal Of Epidemiology 2024, 193: 1115-1126. PMID: 38583942, PMCID: PMC11299032, DOI: 10.1093/aje/kwae038.Peer-Reviewed Original ResearchGrandmother's smokingMother's smokingNurses' Health Study IICohort study subgroupProspective cohort studyNursing reportsOdds ratioNursesCohort studyStudy IISmokingExposure to cigarette smokeCigarette smokingAutism spectrum disorderStudy subgroupsMothersPregnancyMultiple subsequent generationsSpectrum disorderGrandmothersAssociationGrandchildrenAOROddsExposure to environmental insultsChildhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses
Espinosa Dice A, Lawn R, Ratanatharathorn A, Roberts A, Denckla C, Kim A, de la Rosa P, Zhu Y, VanderWeele T, Koenen K. Childhood maltreatment and health in the UK Biobank: triangulation of outcome-wide and polygenic risk score analyses. BMC Medicine 2024, 22: 135. PMID: 38523269, PMCID: PMC10962116, DOI: 10.1186/s12916-024-03360-9.Peer-Reviewed Original ResearchConceptsOutcome-wide analysisUK BiobankBias due to unmeasured confoundingPolygenic risk score analysisPolygenic risk scoresPhysical health outcomesLower household incomeDirection of associationImprove causal inferenceRisk score analysisHearing difficultiesHealth behaviorsHealth outcomesHealth themesUnmeasured confoundersSocioeconomic statusDiastolic blood pressureAnalytic sampleTriangulation studySources of biasHousehold incomeRisk scoreTriangulation designChildhood maltreatmentGeneralized linear modelPolygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence
Ratanatharathorn A, Quan L, Koenen K, Chibnik L, Weisskopf M, Slopen N, Roberts A. Polygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence. Translational Psychiatry 2024, 14: 119. PMID: 38409192, PMCID: PMC10897413, DOI: 10.1038/s41398-024-02814-1.Peer-Reviewed Original ResearchConceptsAttention-deficit hyperactivity disorderAutism spectrum disorderMental illnessIntimate partner violenceBipolar disorderHyperactivity disorderGenetic riskAttention deficit hyperactivity disorderGene-environment correlationPartner violenceDeficit hyperactivity disorderDepressive disorderPolygenic risk scoresSpectrum disorderPolygenic riskNeuroticismMDDDisordersIllnessWomen of European ancestryExperience of intimate partner violenceViolenceSchizophreniaAutismDepression