2022
Association between prevalence of laboratory-identified Clostridioides difficile infection (CDI) and antibiotic treatment for CDI in US acute-care hospitals, 2019
Xu K, Wu H, Li Q, Edwards J, O’Leary E, Leaptrot D, Benin A. Association between prevalence of laboratory-identified Clostridioides difficile infection (CDI) and antibiotic treatment for CDI in US acute-care hospitals, 2019. Infection Control And Hospital Epidemiology 2022, 43: 1847-1852. PMID: 35068404, PMCID: PMC10877317, DOI: 10.1017/ice.2022.6.Peer-Reviewed Original ResearchConceptsClostridioides difficile infectionFirst-line antibioticsAcute care hospitalsCDI prevalenceAntimicrobial useSignificant dose-response associationNational Healthcare Safety NetworkUS acute care hospitalsPositive dose-response relationshipDose-response associationHospital-level variationExtreme discordanceDose-response relationshipMedical school affiliationCDI eventsDifficile infectionAntibiotic treatmentPrevalence ratesHospitalNegative binomial regressionPrevalenceTreatment practicesBinomial regressionInfectionDiscordance
2020
Laboratory Testing, Diagnostic Coding, and Treatment for Electronic Identification of Clostridioides difficile Infection
Stevens V, Benin A, Dantes R, Khader K, Nugent S, Lewis J, Adam T, Zhang R, Fu S, Jones M, Pollock D, Waisbren S. Laboratory Testing, Diagnostic Coding, and Treatment for Electronic Identification of Clostridioides difficile Infection. Infection Control And Hospital Epidemiology 2020, 41: s309-s309. DOI: 10.1017/ice.2020.897.Peer-Reviewed Original ResearchClostridioides difficile infectionPositive laboratory testsOral vancomycinICD codesPositive testElectronic health recordsCDI eventsDifficile infectionDiagnostic codingVeterans Affairs Health SystemHealth recordsProportion of patientsICD-10-CM codesPrior positive testLaboratory testsLong-term carePossibility of treatmentAccompanying treatmentInpatient courseDifficile testingRetrospective cohortTreatment initiationNinth RevisionRecurrent episodesDiagnosis codes