Comparison of Visual and Spectrophotometric Methods of Broth Microdilution MIC End Point Determination and Evaluation of a Sterol Quantitation Method for In Vitro Susceptibility Testing of Fluconazole and Itraconazole against Trailing and Nontrailing Candida Isolates
Arthington-Skaggs BA, Lee-Yang W, Ciblak MA, Frade JP, Brandt ME, Hajjeh RA, Harrison LH, Sofair AN, Warnock A. Comparison of Visual and Spectrophotometric Methods of Broth Microdilution MIC End Point Determination and Evaluation of a Sterol Quantitation Method for In Vitro Susceptibility Testing of Fluconazole and Itraconazole against Trailing and Nontrailing Candida Isolates. Antimicrobial Agents And Chemotherapy 2002, 46: 2477-2481. PMID: 12121921, PMCID: PMC127334, DOI: 10.1128/aac.46.8.2477-2481.2002.Peer-Reviewed Original ResearchConceptsEnd pointSterol quantitation methodActive population-based surveillanceCandida sppPopulation-based surveillanceVisual end pointMIC end pointsC. albicans isolatesAzole antifungal agentsComparison of VisualClinical Laboratory StandardsBloodstream isolatesVitro Susceptibility TestingCandida isolatesSusceptibility testingItraconazoleAlbicans isolatesFluconazoleMIC resultsNational CommitteeVivo outcomesAntifungal agentsGrowth inhibitionC. tropicalisLaboratory StandardsSurveillance for Unexplained Deaths and Critical Illnesses
Hajjeh RA, Relman D, Cieslak PR, Sofair AN, Passaro D, Flood J, Johnson J, Hacker JK, Shieh WJ, Hendry RM, Nikkari S, Ladd-Wilson S, Hadler J, Rainbow J, Tappero JW, Woods CW, Conn L, Reagan S, Zaki S, Perkins BA, Deaths F, Group C. Surveillance for Unexplained Deaths and Critical Illnesses. Emerging Infectious Diseases 2002, 8: 145-153. PMID: 11897065, PMCID: PMC2732455, DOI: 10.3201/eid0802.010165.Peer-Reviewed Original ResearchConceptsCritical illnessMedian ageInfectious causesUnexplained deathEmerging Infections Program sitesPatients' median ageCommon clinical presentationPopulation-based surveillanceYears of ageClinical presentationEpidemiologic featuresPolymerase chain reaction-based methodSerologic testsHealthy personsDiagnostic capacityReaction-based methodsRoutine testingIllnessDeathCauseAgeSurveillanceProgram sitesSyndromeEtiology