Models of Eukaryotic Gradient Sensing: Application to Chemotaxis of Amoebae and Neutrophils
Levchenko A, Iglesias P. Models of Eukaryotic Gradient Sensing: Application to Chemotaxis of Amoebae and Neutrophils. Biophysical Journal 2002, 82: 50-63. PMID: 11751295, PMCID: PMC1302448, DOI: 10.1016/s0006-3495(02)75373-3.Peer-Reviewed Original ResearchConceptsPersistent signalingBiochemical signal transduction pathwaysSmall G proteinsChemotaxis of amoebaeSignal transduction pathwaysG protein activationEukaryotic cellsGradient sensingEukaryotic gradient sensingG proteinsCell typesSignal gradientExquisite precisionChemoattractant gradientPerfect adaptationSignalingAmoebaeActivatorPositive feedbackSensory systemsContinuous presenceAdaptationShallow gradientsChemoattractantInactivator