2019
Accelerated estimation and permutation inference for ACE modeling
Chen X, Formisano E, Blokland G, Strike L, McMahon K, de Zubicaray G, Thompson P, Wright M, Winkler A, Ge T, Nichols T. Accelerated estimation and permutation inference for ACE modeling. Human Brain Mapping 2019, 40: 3488-3507. PMID: 31037793, PMCID: PMC6680147, DOI: 10.1002/hbm.24611.Peer-Reviewed Original ResearchConceptsPermutation inferenceIterative optimizationVariance component modelComputation timeComparable biasAccelerated estimationLinear modelSquared errorCluster sizeSpatial statisticsLinear regression modelsFalse positive riskInferenceHeritability estimationEstimationComponent modelModelWealth of toolsMemory datasetsOptimizationSimple methodSmall numberStatisticsACE modelPermutations
2016
A comprehensive tractography study of patients with bipolar disorder and their unaffected siblings
Sprooten E, Barrett J, McKay DR, Knowles EE, Mathias SR, Winkler AM, Brumbaugh MS, Landau S, Cyr L, Kochunov P, Glahn DC. A comprehensive tractography study of patients with bipolar disorder and their unaffected siblings. Human Brain Mapping 2016, 37: 3474-3485. PMID: 27198848, PMCID: PMC5496097, DOI: 10.1002/hbm.23253.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsBipolar DisorderBrainComorbidityDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFemaleGenetic Predisposition to DiseaseHumansImage Interpretation, Computer-AssistedMaleNeural PathwaysOrgan SizePattern Recognition, AutomatedPsychiatric Status Rating ScalesSeverity of Illness IndexSiblingsYoung Adult