2019
Integrated stepped alcohol treatment for patients with HIV and alcohol use disorder: a randomised controlled trial
Edelman EJ, Maisto SA, Hansen NB, Cutter CJ, Dziura J, Deng Y, Fiellin LE, O'Connor PG, Bedimo R, Gibert CL, Marconi VC, Rimland D, Rodriguez-Barradas MC, Simberkoff MS, Tate JP, Justice AC, Bryant KJ, Fiellin DA. Integrated stepped alcohol treatment for patients with HIV and alcohol use disorder: a randomised controlled trial. The Lancet HIV 2019, 6: e509-e517. PMID: 31109915, PMCID: PMC7161741, DOI: 10.1016/s2352-3018(19)30076-1.Peer-Reviewed Original ResearchConceptsAlcohol use disorderWeek 24Use disordersAlcohol treatmentAdverse eventsNumber of drinksTreatment medicationsPhysician managementAlcohol abuseMental Disorders-IV criteriaAlcohol-related careFormal alcohol treatmentKey exclusion criteriaTimeline followback methodMotivational enhancement therapyTreat populationHIV clinicHIV outcomesPrimary outcomeSpecialty referralsMean ageUS National InstitutesWeek 4Medical conditionsExclusion criteria
2018
Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2018, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.Peer-Reviewed Original ResearchConceptsHIV-positive patientsHeavy drinking daysVACS Index scoreXR-NTXART adherenceDrinking daysIndex scoreUndetectable HIV viral loadCD4 cell countExtended-release naltrexoneDouble-blind placeboHIV viral loadRandomized-controlled trialDrinking outcomesHIV biomarkersSecondary outcomesHIV outcomesPrimary outcomeViral loadAntiretroviral adherenceClinical trialsCell countAlcohol treatmentHIVPatients
2011
Treatment outcomes of a stage 1 cognitive–behavioral trial to reduce alcohol use among human immunodeficiency virus‐infected out‐patients in western Kenya
Papas RK, Sidle JE, Gakinya BN, Baliddawa JB, Martino S, Mwaniki MM, Songole R, Omolo OE, Kamanda AM, Ayuku DO, Ojwang C, Owino‐Ong'or W, Harrington M, Bryant KJ, Carroll KM, Justice AC, Hogan JW, Maisto SA. Treatment outcomes of a stage 1 cognitive–behavioral trial to reduce alcohol use among human immunodeficiency virus‐infected out‐patients in western Kenya. Addiction 2011, 106: 2156-2166. PMID: 21631622, PMCID: PMC3208780, DOI: 10.1111/j.1360-0443.2011.03518.x.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAlcohol useDrinking daysLarge human immunodeficiency virusCognitive behavioral therapy interventionAlcohol intervention studyAlcohol use disorderGroup Cognitive Behavioral Therapy InterventionEffect sizeTreatment effect sizeCognitive behavioral therapyDual epidemicsRandomized participantsPatient clinicImmunodeficiency virusPreliminary efficacyHuman immunodeficiencyClinical trialsTreatment outcomesAlcohol abstinenceAssessment-only controlBinge drinkingUse disordersTherapy interventionFeasible intervention
2009
Systematic Cultural Adaptation of Cognitive-Behavioral Therapy to Reduce Alcohol Use Among HIV-Infected Outpatients in Western Kenya
Papas RK, Sidle JE, Martino S, Baliddawa JB, Songole R, Omolo OE, Gakinya BN, Mwaniki MM, Adina JO, Nafula T, Owino-Ong’or W, Bryant KJ, Carroll KM, Goulet JL, Justice AC, Maisto SA. Systematic Cultural Adaptation of Cognitive-Behavioral Therapy to Reduce Alcohol Use Among HIV-Infected Outpatients in Western Kenya. AIDS And Behavior 2009, 14: 669-678. PMID: 19967441, PMCID: PMC2949418, DOI: 10.1007/s10461-009-9647-6.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAlcohol useSystematic cultural adaptationGeneral medicine outpatientsPilot feasibility studyCognitive behavioral therapyARV adherenceTreatment satisfactionPreliminary efficacyHIV epidemicWestern KenyaCultural adaptationHIVHazardous drinkingBehavioral treatmentCBT sessionsOutpatientsMedicine outpatientsOverall attendanceStrong efficacyPercent daysRisky sexSession 6Two-thirdsEffect size
2008
Depression Symptoms and Treatment Among HIV Infected and Uninfected Veterans
Sueoka K, Goulet JL, Fiellin DA, Rimland D, Butt AA, Gibert C, Rodriguez-Barradas MC, Bryant K, Crystal S, Justice AC. Depression Symptoms and Treatment Among HIV Infected and Uninfected Veterans. AIDS And Behavior 2008, 14: 272-279. PMID: 18648927, PMCID: PMC3125603, DOI: 10.1007/s10461-008-9428-7.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudySelective serotonin reuptake inhibitorsDepressive symptomsMental health providersDepression treatmentHealth providersPatient Health Questionnaire scoresActive depressive symptomsAging Cohort StudySerotonin reuptake inhibitorsCommon comorbid conditionsNon-Hispanic whitesHIV providersUninfected subjectsUninfected veteransCohort studyProspective cohortReuptake inhibitorsComorbid conditionsHIV statusPrimary careMental health counselingMultivariable modelQuestionnaire scoresDepression symptoms