2020
Excess Weight Gain After Cure of Hepatitis C Infection with Direct-Acting Antivirals
Do A, Esserman DA, Krishnan S, Lim JK, Taddei TH, Hauser RG, Tate JP, Re VL, Justice AC. Excess Weight Gain After Cure of Hepatitis C Infection with Direct-Acting Antivirals. Journal Of General Internal Medicine 2020, 35: 2025-2034. PMID: 32342483, PMCID: PMC7352003, DOI: 10.1007/s11606-020-05782-6.Peer-Reviewed Original ResearchConceptsDAA treatmentExcess weight gainTreatment initiationWeight gainChronic hepatitis C virus (HCV) infectionHigh FIB-4 scoreHepatitis C virus infectionC virus infectionFIB-4 scoreHepatitis C infectionDirect acting antiviralsLiver disease progressionMultiple logistic regressionConclusionWeight gainDAA therapySVR achievementC infectionBaseline weightProspective studyExcess weightDisease progressionVirus infectionHigh riskPatientsBirth cohort
2016
Weight Gain and Incident Diabetes Among HIV-Infected Veterans Initiating Antiretroviral Therapy Compared With Uninfected Individuals
Herrin M, Tate JP, Akgün KM, Butt AA, Crothers K, Freiberg MS, Gibert CL, Leaf DA, Rimland D, Rodriguez-Barradas MC, Ruser CB, Herold KC, Justice AC. Weight Gain and Incident Diabetes Among HIV-Infected Veterans Initiating Antiretroviral Therapy Compared With Uninfected Individuals. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 73: 228-236. PMID: 27171741, PMCID: PMC5023454, DOI: 10.1097/qai.0000000000001071.Peer-Reviewed Original ResearchConceptsRisk of DMVeterans Aging Cohort StudyAntiretroviral therapyAging Cohort StudyDiabetes mellitusBody mass indexUninfected individualsWeight gainART initiationIncident diabetesCohort studyHazard ratioMass indexIncident type 2 diabetes mellitusAvailable body mass indexBaseline body mass indexType 2 diabetes mellitusNational observational studyConfidence intervalsSubstantial weight gainHIV infectionCox regressionPounds of weightObservational studyLow prevalence
2015
Rising Obesity Prevalence and Weight Gain Among Adults Starting Antiretroviral Therapy in the United States and Canada
Koethe JR, Jenkins CA, Lau B, Shepherd BE, Justice AC, Tate JP, Buchacz K, Napravnik S, Mayor AM, Horberg MA, Blashill AJ, Willig A, Wester CW, Silverberg MJ, Gill J, Thorne JE, Klein M, Eron JJ, Kitahata MM, Sterling TR, Moore RD. Rising Obesity Prevalence and Weight Gain Among Adults Starting Antiretroviral Therapy in the United States and Canada. AIDS Research And Human Retroviruses 2015, 32: 50-58. PMID: 26352511, PMCID: PMC4692122, DOI: 10.1089/aid.2015.0147.Peer-Reviewed Original ResearchConceptsYears of ARTBody mass indexAntiretroviral therapyART initiationMedian body mass indexNormal body mass indexHigher body mass indexWeight gainWhite womenUnited States National HealthART-exposed HIVHIV-1 RNAProportion of overweightMultivariable linear regressionCohort CollaborationNA-ACCORDNon-white womenCohort studyMedian ageObese adultsMass indexObesity prevalenceNational HealthHigh prevalenceHealth complicationsWeight Change After Antiretroviral Therapy and Mortality
Yuh B, Tate J, Butt AA, Crothers K, Freiberg M, Leaf D, Logeais M, Rimland D, Rodriguez-Barradas MC, Ruser C, Justice AC. Weight Change After Antiretroviral Therapy and Mortality. Clinical Infectious Diseases 2015, 60: 1852-1859. PMID: 25761868, PMCID: PMC4542664, DOI: 10.1093/cid/civ192.Peer-Reviewed Original ResearchConceptsBaseline body mass indexVeterans Aging Cohort StudyNormal weight patientsART initiationWeight gainWeight changeHuman immunodeficiency virus-infected patientsLower mortalityDisease severityAntiretroviral therapy initiationMultivariable Cox modelVirus-infected patientsAging Cohort StudyMedian weight changeBody mass indexYears of ARTGreater disease severityVACS IndexAntiretroviral therapyTherapy initiationBaseline weightCohort studyObese patientsSurvival benefitHemoglobin levels