2020
T Lymphocyte Subsets Associated With Prevalent Diabetes in Veterans With and Without Human Immunodeficiency Virus
Bailin SS, McGinnis KA, McDonnell WJ, So-Armah K, Wellons M, Tracy RP, Doyle MF, Mallal S, Justice AC, Freiberg MS, Landay AL, Wanjalla C, Koethe JR. T Lymphocyte Subsets Associated With Prevalent Diabetes in Veterans With and Without Human Immunodeficiency Virus. The Journal Of Infectious Diseases 2020, 222: 252-262. PMID: 32052044, PMCID: PMC7323499, DOI: 10.1093/infdis/jiaa069.Peer-Reviewed Original ResearchConceptsT cell subsetsT cellsMemory CD4Prevalent diabetesMemory T cell expansionVeterans Aging Cohort StudyMultivariable logistic regression modelHuman immunodeficiency virus (HIV) populationPrevalent diabetes casesPrevalent diabetes mellitusChronic immune activationHIV-negative individualsHIV-negative participantsT lymphocyte subsetsPrevalence of diabetesTraditional risk factorsAging Cohort StudyHuman immunodeficiency virusT cell expansionLogistic regression modelsCytomegalovirus serostatusLymphocyte subsetsCohort studyDiabetes mellitusHIV status
2017
Effect of Immediate Initiation of Antiretroviral Treatment in HIV-Positive Individuals Aged 50 Years or Older
Lodi S, Costagliola D, Sabin C, del Amo J, Logan R, Abgrall S, Reiss P, van Sighem A, Jose S, Blanco JR, Hernando V, Bucher HC, Kovari H, Segura F, Ambrosioni J, Gogos CA, Pantazis N, Dabis F, Vandenhende MA, Meyer L, Seng R, Gill MJ, Krentz H, Phillips AN, Porter K, Grinsztejn B, Pacheco AG, Muga R, Tate J, Justice A, Hernán MA. Effect of Immediate Initiation of Antiretroviral Treatment in HIV-Positive Individuals Aged 50 Years or Older. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 76: 311-318. PMID: 28746165, PMCID: PMC5704899, DOI: 10.1097/qai.0000000000001498.Peer-Reviewed Original ResearchConceptsGeneral HIV populationImmediate initiationHIV populationCD4 countCells/US veteransAIDS mortalityAIDS-free individualsNon-AIDS mortalityUS Veteran cohortHIV-positive individualsHIV-CAUSAL CollaborationAntiretroviral therapyCause mortalityAntiretroviral treatmentMedian ageClinical guidelinesVeteran cohortHigh mortalityMortalityCD4Younger participantsRiskBaselineVeterans
2015
Do Alcohol Misuse, Smoking, and Depression Vary Concordantly or Sequentially? A Longitudinal Study of HIV-Infected and Matched Uninfected Veterans in Care
Braithwaite RS, Fang Y, Tate J, Mentor SM, Bryant KJ, Fiellin DA, Justice AC. Do Alcohol Misuse, Smoking, and Depression Vary Concordantly or Sequentially? A Longitudinal Study of HIV-Infected and Matched Uninfected Veterans in Care. AIDS And Behavior 2015, 20: 566-572. PMID: 26187007, PMCID: PMC5009622, DOI: 10.1007/s10461-015-1117-8.Peer-Reviewed Original ResearchConceptsHarmful alcohol useAlcohol misuseCurrent smokingVeterans Aging Cohort StudyAlcohol useAging Cohort StudyUninfected veteransCohort studyHIV statusDepression variesChronic diseasesCommon syndromePrior depressionSmokingUninfected individualsCurrent depressionHIVDepressionLongitudinal studyRegression analysisCareVeteransMisuseSame surveyNumber of years
2013
Physiologic Frailty and Fragility Fracture in HIV-Infected Male Veterans
Womack JA, Goulet JL, Gibert C, Brandt CA, Skanderson M, Gulanski B, Rimland D, Rodriguez-Barradas MC, Tate J, Yin MT, Justice AC, Team F. Physiologic Frailty and Fragility Fracture in HIV-Infected Male Veterans. Clinical Infectious Diseases 2013, 56: 1498-1504. PMID: 23378285, PMCID: PMC3634308, DOI: 10.1093/cid/cit056.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesFractures, BoneHIV InfectionsHumansMaleMiddle AgedProportional Hazards ModelsRegression AnalysisUnited StatesVeteransConceptsHuman immunodeficiency virusVACS Index scoreFragility fracturesPhysiologic frailtyVACS IndexMale veteransInhibitor useFracture riskRisk factorsVeterans Aging Cohort Study (VACS) IndexIndex scoreFragility fracture risk factorsICD-9-CM codesProtease inhibitor useFracture risk factorsMarkers of inflammationBody mass indexUpper arm fracturesAlcohol-related diagnosesCox regression modelFirst fragility fractureCause mortalityHIV RNAHemoglobin levelsMass index
2011
Treatment outcomes of a stage 1 cognitive–behavioral trial to reduce alcohol use among human immunodeficiency virus‐infected out‐patients in western Kenya
Papas RK, Sidle JE, Gakinya BN, Baliddawa JB, Martino S, Mwaniki MM, Songole R, Omolo OE, Kamanda AM, Ayuku DO, Ojwang C, Owino‐Ong'or W, Harrington M, Bryant KJ, Carroll KM, Justice AC, Hogan JW, Maisto SA. Treatment outcomes of a stage 1 cognitive–behavioral trial to reduce alcohol use among human immunodeficiency virus‐infected out‐patients in western Kenya. Addiction 2011, 106: 2156-2166. PMID: 21631622, PMCID: PMC3208780, DOI: 10.1111/j.1360-0443.2011.03518.x.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAlcohol useDrinking daysLarge human immunodeficiency virusCognitive behavioral therapy interventionAlcohol intervention studyAlcohol use disorderGroup Cognitive Behavioral Therapy InterventionEffect sizeTreatment effect sizeCognitive behavioral therapyDual epidemicsRandomized participantsPatient clinicImmunodeficiency virusPreliminary efficacyHuman immunodeficiencyClinical trialsTreatment outcomesAlcohol abstinenceAssessment-only controlBinge drinkingUse disordersTherapy interventionFeasible intervention
2010
HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era
Crothers K, Huang L, Goulet JL, Goetz MB, Brown ST, Rodriguez-Barradas MC, Oursler KK, Rimland D, Gibert CL, Butt AA, Justice AC. HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era. American Journal Of Respiratory And Critical Care Medicine 2010, 183: 388-395. PMID: 20851926, PMCID: PMC3266024, DOI: 10.1164/rccm.201006-0836oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseCombination antiretroviral therapy eraAntiretroviral therapy eraPulmonary diseaseTherapy eraPulmonary infectionHIV infectionVeterans Aging Cohort Study Virtual CohortIncident chronic obstructive pulmonary diseaseLower HIV RNA levelsVirtual cohortVeterans Affairs Healthcare SystemAssociation of HIVMost pulmonary diseasesHIV RNA levelsRates of asthmaIncidence rate ratiosSelf-reported smokingLarge Health SurveyPulmonary hypertensionUninfected patientsComorbid diseasesOpportunistic pneumoniaBacterial pneumonia
2004
Association of venous thromboembolism with human immunodeficiency virus and mortality in veterans
Fultz SL, McGinnis KA, Skanderson M, Ragni MV, Justice AC. Association of venous thromboembolism with human immunodeficiency virus and mortality in veterans. The American Journal Of Medicine 2004, 116: 420-423. PMID: 15006592, DOI: 10.1016/j.amjmed.2003.10.011.Peer-Reviewed Original Research
2001
Development and validation of a self-completed HIV symptom index
Justice AC, Holmes W, Gifford AL, Rabeneck L, Zackin R, Sinclair G, Weissman S, Neidig J, Marcus C, Chesney M, Cohn SE, Wu AW, Committee F. Development and validation of a self-completed HIV symptom index. Journal Of Clinical Epidemiology 2001, 54: s77-s90. PMID: 11750213, DOI: 10.1016/s0895-4356(01)00449-8.Peer-Reviewed Original ResearchConceptsHIV Symptom IndexCD4 cell countSymptom IndexPatient-oriented researchProspective sampleClinical managementCleveland Veterans Affairs Medical CenterCell countDisease severityAIDS Clinical Trials GroupMental health summary scoresVeterans Affairs Medical CenterViral quantificationAdverse drug event reportingAdverse drug reportingExcellent completion ratesMultidrug antiretroviral therapyPatient-reported symptomsHealth-related qualityConvenience sampleClinical Trials GroupHealth summary scoresPhysician-assessed disease severityChi-square testAntiretroviral therapyPatient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence
Wagner JH, Justice AC, Chesney M, Sinclair G, Weissman S, Rodriguez-Barradas M, Team F. Patient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence. Journal Of Clinical Epidemiology 2001, 54: s91-s98. PMID: 11750214, DOI: 10.1016/s0895-4356(01)00450-4.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestViral loadProvider assessmentCurrent drug useDepressive symptomsCurrent alcohol usePatient reportsDrug useAlcohol useIndependent associationVeterans Affairs Health Care SystemPatient-reported adherenceCurrent viral loadPharmacy refill dataAntiretroviral medication adherenceEpidemiological Studies DepressionIllicit drug useDisorders Identification TestElectronic laboratory dataHealth care systemRefill dataMedication adherencePatient adherenceAntiretroviral adherenceMultivariate regression model