A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease
Vanasse GJ, Jeong JY, Tate J, Bathulapalli H, Anderson D, Steen H, Fleming M, Mattocks K, Telenti A, Fellay J, Justice AC, Berliner N. A polymorphism in the leptin gene promoter is associated with anemia in patients with HIV disease. Blood 2011, 118: 5401-5408. PMID: 21926355, PMCID: PMC3217345, DOI: 10.1182/blood-2011-06-362194.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyCombined antiretroviral therapyPrevalence of anemiaHIV diseaseSingle nucleotide polymorphismsModern combined antiretroviral therapyWorld Health Organization criteriaAging Cohort StudyA Single Nucleotide PolymorphismGene single nucleotide polymorphismsLeptin gene promoterHIV subjectsAntiretroviral therapyCohort studyHIV statusOrganization criteriaClinical dataIndependent cohortAnemiaHIVPatientsLeptin genePrevalenceDiseaseCandidate gene approach