2012
HIV infection, aging, and immune function
Dubrow R, Silverberg MJ, Park LS, Crothers K, Justice AC. HIV infection, aging, and immune function. Current Opinion In Oncology 2012, 24: 506-516. PMID: 22759737, PMCID: PMC3695478, DOI: 10.1097/cco.0b013e328355e131.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV infectionCancer riskCancer preventionMore effective antiretroviral therapySustained antiretroviral therapyCombination antiretroviral therapyEffective antiretroviral therapyCancer risk factorsComplex chronic diseaseImmune system effectsSpecific cancer typesSystemic inflammationImmune dysfunctionChronic inflammationViral causeSmoking effectsLung cancerIndependent associationRisk factorsChronic diseasesHigh prevalenceCancer spectrumLiver cancerElevated risk
2010
HIV and Aging: Time for a New Paradigm
Justice A. HIV and Aging: Time for a New Paradigm. Current HIV/AIDS Reports 2010, 7: 69-76. PMID: 20425560, DOI: 10.1007/s11904-010-0041-9.Peer-Reviewed Original ResearchConceptsHIV infectionNon-AIDS diseasesCombination antiretroviral therapyPopulation of patientsCause of morbidityComplex chronic diseaseSpectrum of diseaseProlong life expectancyAntiretroviral therapyCD4 countHIV RNAViral suppressionFunctional statusChronic diseasesPatient riskOptimal managementHIVInfectionLife expectancyDiseaseMorbidityMortalityAIDSRiskPatients