2012
Functional analysis of erythrocyte determinants of Plasmodium infection
Bei AK, Duraisingh MT. Functional analysis of erythrocyte determinants of Plasmodium infection. International Journal For Parasitology 2012, 42: 575-582. PMID: 22726752, PMCID: PMC3383627, DOI: 10.1016/j.ijpara.2012.03.006.Peer-Reviewed Original ResearchConceptsFunctional analysisErythrocyte determinantsObligate intracellular pathogensPlasmodium infectionTransgenic approachesHuman erythrocytes resultsNatural variationErythrocyte invasionIntracellular pathogensPlasmodium falciparum parasitesUnexplored frontierClinical manifestationsMalaria researchErythrocytes resultsFalciparum parasitesInvasionMalarial diseaseChemical biologicalInfectionErythrocytesParasitesPathogensDeterminantsRemodellingDiscovery
2010
In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection
Bei AK, Brugnara C, Duraisingh MT. In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection. The Journal Of Infectious Diseases 2010, 202: 1722-1727. PMID: 20958212, PMCID: PMC3107553, DOI: 10.1086/657157.Peer-Reviewed Original ResearchConceptsGenetic analysisErythrocyte determinantsSystematic functional analysisDirect genetic analysisErythrocyte biologyInvasion of erythrocytesIsogenic backgroundP. falciparum invasionGene expressionFunctional analysisParasite invasionObligatory stepLentiviral transductionHost receptorsGlycophorin ALife cyclePlasmodium falciparumCulture systemInvasionMalaria infectionUnambiguous identificationTransductionBiologyParasitesErythrocytes