An update on type 2B von Willebrand disease
Mikhail S, Aldin ES, Streiff M, Zeidan A. An update on type 2B von Willebrand disease. Expert Review Of Hematology 2014, 7: 217-231. PMID: 24521271, DOI: 10.1586/17474086.2014.868771.Peer-Reviewed Original ResearchConceptsVon Willebrand diseaseType 2B von Willebrand diseaseVon Willebrand factorAbnormal von Willebrand factorWillebrand diseaseHigh molecular weight VWF multimersSignificant clinical variationWeight VWF multimersPlatelet countPlatelet transfusionsReplacement therapyPlatelet clearanceVWD patientsTransient decreaseClinical variationFactor VIIIWillebrand factorDiseaseVWF multimersPatientsIdentical mutationsSuboptimal resultsTransfusionDesmopressinPreferential loss