Effect of availability of oral iron chelation therapy (ICT) on initiation, duration, and dose adequacy in patients with myelodysplastic syndromes (MDS) and transfusional iron overload (TIO).
Gore S, Davidoff A, Hendrick F, Duong V, Stuart B, Baer M, Shenolikar R, Zeidan A. Effect of availability of oral iron chelation therapy (ICT) on initiation, duration, and dose adequacy in patients with myelodysplastic syndromes (MDS) and transfusional iron overload (TIO). Journal Of Clinical Oncology 2013, 31: e17584-e17584. DOI: 10.1200/jco.2013.31.15_suppl.e17584.Peer-Reviewed Original ResearchOral iron chelation therapyIron chelation therapyTransfusional iron overloadMyelodysplastic syndromeDose adequacySupportive care drugsProportional hazards modelMedicare Part ATherapeutic equipoiseCohort entryHazard ratioMost patientsRBC transfusionMDS patientsOral chemotherapyAdequate doseCare drugsIron overloadLogistics of administrationChelation therapyOral formulationHazards modelMedicare beneficiariesParenteral administrationTreatment duration