2021
Disparity in utilization of multiagent therapy for acute promyelocytic leukemia (APL): A large National Cancer Database (NCDB) analysis.
Dhakal P, Lyden E, Gundabolu K, Zeidan A, Loh K, Fisher A, Bhatt V. Disparity in utilization of multiagent therapy for acute promyelocytic leukemia (APL): A large National Cancer Database (NCDB) analysis. Journal Of Clinical Oncology 2021, 39: 6587-6587. DOI: 10.1200/jco.2021.39.15_suppl.6587.Peer-Reviewed Original ResearchSingle-agent therapyAcute promyelocytic leukemiaCommunity cancer centerMultiagent therapyAgent therapyCancer CenterReal-world practiceUninsured patientsClinical trialsComprehensive community cancer centerNational Cancer Database AnalysisMultiple logistic regression analysisFindings highlight disparitiesLower comorbidity indexThird of patientsAcademic cancer centerAppropriateness of treatmentHealth system factorsAcute myeloid leukemiaLogistic regression analysisUnknown therapyComorbidity indexGreater comorbidityMultiagent chemotherapyOverall survival
2018
Does Provider Experience Treating Patients (pts) with Myelodysplastic Syndromes (MDS) Explain Duration of Hypomethylating Agent (HMA) Therapy and Overall Survival (OS)? A Large Population-Based Analysis
Zeidan A, Hu X, Zhu W, Stahl M, Giri S, Huntington S, Wang R, Podoltsev N, Gore S, Ma X, Davidoff A. Does Provider Experience Treating Patients (pts) with Myelodysplastic Syndromes (MDS) Explain Duration of Hypomethylating Agent (HMA) Therapy and Overall Survival (OS)? A Large Population-Based Analysis. Blood 2018, 132: 370. DOI: 10.1182/blood-2018-99-111052.Peer-Reviewed Original ResearchHMA cyclesOverall survivalHMA initiationHMA therapyMyelodysplastic syndromeProvider typeCancer CenterMD volumeMultivariate Cox proportional hazardsKaplan-Meier log-rank testAZA-001 trialMedian overall survivalTwo-sided statistical testsLog-rank testReal-world survivalCox proportional hazardsLogistic regression analysisWilcoxon rank sum testChi-square testCommunity-based practiceRank sum testEligible ptsLookback periodEarly discontinuationAgent therapy
2017
Relationship between Hospital Volume and Inpatient Mortality Among Patients Diagnosed with Thrombotic Thrombocytopenic Purpura (TTP) in the United States
Giri S, Pathak R, Franklin R, Podoltsev N, Huntington S, Mehta K, Zeidan A. Relationship between Hospital Volume and Inpatient Mortality Among Patients Diagnosed with Thrombotic Thrombocytopenic Purpura (TTP) in the United States. Blood 2017, 130: 675. DOI: 10.1182/blood.v130.suppl_1.675.675.Peer-Reviewed Original ResearchThrombotic thrombocytopenic purpuraHospital volumeInpatient mortality rateNationwide Inpatient SampleInpatient mortalityThrombocytopenic purpuraPotential confoundersMortality rateOverall inpatient mortality rateInitiation of plasmapheresisUnique hospital identifiersHigher inpatient mortalityRetrospective cohort studyHigh-volume hospitalsAdjusted odds ratioLogistic regression analysisHierarchical logistic regression analysisTest of trendUnique hospitalizationsHospital mortalityInpatient outcomesHospital courseTotal hospitalizationsVolume hospitalsAdult patientsHealth Care Use by Older Adults With Acute Myeloid Leukemia at the End of Life
Wang R, Zeidan AM, Halene S, Xu X, Davidoff AJ, Huntington SF, Podoltsev NA, Gross CP, Gore SD, Ma X. Health Care Use by Older Adults With Acute Myeloid Leukemia at the End of Life. Journal Of Clinical Oncology 2017, 35: jco.2017.72.714. PMID: 28783450, PMCID: PMC5648174, DOI: 10.1200/jco.2017.72.7149.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaDays of lifeEnd of lifeLife careHospice careOlder patientsHospice enrollmentMyeloid leukemiaIntensive care unit admissionMultivariable logistic regression analysisOlder adultsLate hospice enrollmentCare unit admissionRetrospective cohort studyUse of chemotherapyIntensive care unitHealth care useLogistic regression analysisYears of ageUnit admissionAggressive treatmentCohort studyOverall cohortAML diagnosisCare unit