Early life adversity alters normal sex-dependent developmental dynamics of DNA methylation
Massart R, Nemoda Z, Suderman MJ, Sutti S, Ruggiero AM, Dettmer AM, Suomi SJ, Szyf M. Early life adversity alters normal sex-dependent developmental dynamics of DNA methylation. Development And Psychopathology 2016, 28: 1259-1272. PMID: 27687908, PMCID: PMC6590057, DOI: 10.1017/s0954579416000833.Peer-Reviewed Original ResearchConceptsDNA methylation profilesDNA methylation changesMethylation profilesMethylation changesGenome-wide DNA methylation changesEpigenetic programsDevelopmental evolutionEpigenetic processesDNA methylationAdult phenotypeDevelopmental dynamicsNormal evolutionGenesMethylationEvolutionPhenotypeEarly life eventsEarly life experiencesEffects of sexFemalesEarly life adversityT lymphocytesNonhuman primatesRodentsPrimates