Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates
Leak RK, Garbett KA, Dettmer AM, Zhang Z, Mirnics K, Cameron JL. Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates. Cell And Tissue Research 2012, 350: 401-407. PMID: 22940761, PMCID: PMC3779886, DOI: 10.1007/s00441-012-1488-3.Peer-Reviewed Original ResearchConceptsImpact of exercisePhysical activityTyrosine hydroxylaseParkinson's diseaseSpontaneous activitySpontaneous physical activityDopaminergic neurotoxin MPTPOverall physical activityPlasma ceruloplasmin levelsParkinsonian primatesUnilateral lossTreadmill exerciseDopaminergic phenotypeNeurotoxin MPTPParkinson modelIntact monkeysCeruloplasmin levelsCeruloplasmin expressionNeurodegenerative conditionsMPTPOverall daily activityActive lifestyleRhesus monkeysTreadmill activityExperimental model