Seizures and Sleep in the Thalamus: Focal Limbic Seizures Show Divergent Activity Patterns in Different Thalamic Nuclei
Feng L, Motelow JE, Ma C, Biche W, McCafferty C, Smith N, Liu M, Zhan Q, Jia R, Xiao B, Duque A, Blumenfeld H. Seizures and Sleep in the Thalamus: Focal Limbic Seizures Show Divergent Activity Patterns in Different Thalamic Nuclei. Journal Of Neuroscience 2017, 37: 11441-11454. PMID: 29066556, PMCID: PMC5700426, DOI: 10.1523/jneurosci.1011-17.2017.Peer-Reviewed Original ResearchConceptsFocal limbic seizuresLimbic seizuresCentral lateralDifferent thalamic nucleiSeizure propagationThalamic nucleiNeuronal activityDivergent activity patternsFocal temporal lobe seizuresDepressed cortical functionDifferent thalamic regionsLimbic seizure propagationTemporal lobe seizuresFemale rat modelTemporal lobe epilepsySleep spindlesImpairment of consciousnessSubcortical arousal systemsVentral posteromedial nucleusSlow-wave sleepOverall firing rateQuality of lifeThalamocortical network activityThalamocortical information flowActivity patterns