The History of Engineered Tracheal Replacements: Interpreting the Past and Guiding the Future
Greaney A, Niklason L. The History of Engineered Tracheal Replacements: Interpreting the Past and Guiding the Future. Tissue Engineering Part B Reviews 2020, 27: 341-352. PMID: 33045942, PMCID: PMC8390779, DOI: 10.1089/ten.teb.2020.0238.Peer-Reviewed Original ResearchConceptsFailure modesTracheal graftsTracheal replacementGraft mechanicsDesign criteriaInert materialLong segment defectType of graftRecent preclinical workClinical care prioritiesRigid tubeLeuven protocolTracheal allograftsClinical followAirway reconstructionCadaveric allograftsCircumferential defectsTissue analysis techniquesEngineersPreclinical workReplacement graftsCare prioritiesGraft performanceHuman patientsGraft