2023
Rational engineering of lung alveolar epithelium
Leiby K, Yuan Y, Ng R, Raredon M, Adams T, Baevova P, Greaney A, Hirschi K, Campbell S, Kaminski N, Herzog E, Niklason L. Rational engineering of lung alveolar epithelium. Npj Regenerative Medicine 2023, 8: 22. PMID: 37117221, PMCID: PMC10147714, DOI: 10.1038/s41536-023-00295-2.Peer-Reviewed Original Research
2021
A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds
Yuan Y, Leiby KL, Greaney AM, Raredon MSB, Qian H, Schupp JC, Engler AJ, Baevova P, Adams TS, Kural MH, Wang J, Obata T, Yoder MC, Kaminski N, Niklason LE. A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds. Frontiers In Bioengineering And Biotechnology 2021, 9: 760309. PMID: 34869270, PMCID: PMC8640093, DOI: 10.3389/fbioe.2021.760309.Peer-Reviewed Original ResearchVascular diseaseEndothelial phenotypeLung vascular diseaseAcute lung injuryPulmonary microvascular functionWhole lung scaffoldsVascular barrier functionLung injuryMicrovascular functionEndothelial cell coverageSingle-cell RNA-sequencing analysisLPS treatmentProinflammatory signalsWhole lungLung endotheliumLung systemVascular barrierOrgan engineering approachesBarrier functionLungWhole-organ scaffoldsVascular structuresDrug mechanismsEndotheliumDisease
2020
Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019
Wagner D, Ikonomou L, Gilpin S, Magin C, Cruz F, Greaney A, Magnusson M, Chen Y, Davis B, Vanuytsel K, Enes S, Krasnodembskaya A, Lehmann M, Westergren-Thorsson G, Stegmayr J, Alsafadi H, Hoffman E, Weiss D, Ryan A. Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019. ERJ Open Research 2020, 6: 00123-2020. PMID: 33123557, PMCID: PMC7569162, DOI: 10.1183/23120541.00123-2020.Peer-Reviewed Original ResearchCell therapyProgenitor cellsLung stemLung biologyInduced pluripotent stem cell modelsInternational Society for CellTreatment of lung diseasesPluripotent stem cell modelsPulmonary Fibrosis FoundationCystic Fibrosis FoundationStem cell modelRegenerative medicine productsAlpha-1 FoundationUniversity of Vermont Larner College of MedicineGene therapyCystic fibrosisLung diseaseCollege of MedicineTherapyStem cellsAlpha 1LungBlood InstituteNational HeartExtracellular vesicles