2024
Quadrivalent Conjugate Vaccine and Invasive Meningococcal Disease in US Adolescents and Young Adults
Shin T, Wells C, Shoukat A, Potter-Schwartz L, Langevin E, Langley J, Galvani A, Moghadas S. Quadrivalent Conjugate Vaccine and Invasive Meningococcal Disease in US Adolescents and Young Adults. JAMA Network Open 2024, 7: e2443551. PMID: 39504021, PMCID: PMC11541638, DOI: 10.1001/jamanetworkopen.2024.43551.Peer-Reviewed Original ResearchConceptsInvasive meningococcal diseaseInvasive meningococcal disease casesCases of invasive meningococcal diseaseQuadrivalent conjugate vaccineUS adolescentsMeningococcal diseaseConjugate vaccineMenACWY vaccineIncidence rates of invasive meningococcal diseasePrevention of invasive meningococcal diseaseIncidence rateBurden of meningococcal diseaseUS adolescent populationUS populationYoung adultsImmunization of adolescentsIncidence of invasive meningococcal diseaseBayesian hierarchical Poisson regression modelsDecision analytical studyRate of invasive meningococcal diseaseMenACWY vaccination programUnvaccinated individualsDecision analytic modelHierarchical Poisson regression modelYears of age
2015
Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts
Bellan SE, Dushoff J, Galvani AP, Meyers LA. Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts. PLOS Medicine 2015, 12: e1001801. PMID: 25781323, PMCID: PMC4363602, DOI: 10.1371/journal.pmed.1001801.Peer-Reviewed Original ResearchConceptsElevated viral loadAcute phaseViral load trajectoriesSexual network structureViral loadStudy terminationExclusion criteriaRetrospective cohort study designStudy designAcute phase durationSerodiscordant heterosexual couplesRetrospective cohort dataCohort study designProportion of transmissionCourse of infectionRetrospective cohortAntiretroviral treatmentSerodiscordant couplesChronic phaseSimulated cohortRelative hazardCohort dataCohortWide credibility intervalsAdditional risk