2012
Sleep Problems in Children with Sickle Cell Disease
Khatwa U, Bazzy-Asaad A, Kothare S. Sleep Problems in Children with Sickle Cell Disease. Respiratory Medicine 2012, 323-336. DOI: 10.1007/978-1-60761-725-9_24.Peer-Reviewed Original ResearchSleep-disordered breathingSickle cell diseaseSleep problemsCell diseaseUpper airway obstructionGeneral pediatric populationVaso-occlusive crisisCommon sleep problemsNocturnal hypoxemiaAirway obstructionPulmonary hypertensionAdenotonsillar hypertrophySecondary hyperplasiaSplenic infarctionClinical presentationPediatric populationLymphoid tissuePrevalent hemoglobinopathyOxyhemoglobin saturationTreatment strategiesExtramedullary hematopoiesisPulse oximetryHypoxemiaChildrenDisease
2009
Longitudinal follow up of elevated pulmonary artery pressures in children with sickle cell disease
Pashankar FD, Carbonella J, Bazzy‐Asaad A, Friedman A. Longitudinal follow up of elevated pulmonary artery pressures in children with sickle cell disease. British Journal Of Haematology 2009, 144: 736-741. PMID: 19055665, DOI: 10.1111/j.1365-2141.2008.07501.x.Peer-Reviewed Original ResearchConceptsTricuspid regurgitant jet velocityElevated pulmonary artery pressurePulmonary artery pressureSickle cell diseaseArtery pressureCell diseaseHigher tricuspid regurgitant jet velocityObstructive sleep apneaRegurgitant jet velocityRight ventricular pressureLowest oxygen saturationBorderline elevationCardiopulmonary evaluationInitial echocardiogramRepeat echocardiogramPulmonary hypertensionLower hemoglobinSleep apneaPersistent elevationRisk factorsVentricular pressureIntrapatient variabilityOxygen saturationEchocardiogramPatients
2008
Prevalence and Risk Factors of Elevated Pulmonary Artery Pressures in Children With Sickle Cell Disease
Pashankar FD, Carbonella J, Bazzy-Asaad A, Friedman A. Prevalence and Risk Factors of Elevated Pulmonary Artery Pressures in Children With Sickle Cell Disease. Pediatrics 2008, 121: 777-782. PMID: 18381543, DOI: 10.1542/peds.2007-0730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge DistributionAnemia, Sickle CellChildChild, PreschoolCohort StudiesComorbidityFemaleFollow-Up StudiesHumansHypertension, PulmonaryMaleMass ScreeningPrevalenceProspective StudiesPulmonary Wedge PressureRisk AssessmentSeverity of Illness IndexSex DistributionSurvival AnalysisTricuspid Valve InsufficiencyUltrasonography, Doppler, TranscranialConceptsTricuspid regurgitant jet velocityElevated pulmonary artery pressureElevated tricuspid regurgitant jet velocityPulmonary artery pressureRegurgitant jet velocityTranscranial Doppler examinationArtery pressurePulmonary hypertensionDoppler examinationSickle cell diseaseRisk factorsCell diseaseExact testPeak tricuspid regurgitant jet velocityPulmonary artery systolic pressureHigh pulmonary artery pressureComprehensive clinic visitModerate pulmonary hypertensionRight outflow obstructionAcute chest syndromeMild pulmonary hypertensionPercent of patientsChronic blood transfusionsHigher platelet countsLowest oxygen saturation