Spatiotemporal Organization of Prefrontal Norepinephrine Influences Neuronal Activity
Glaeser-Khan S, Savalia N, Cressy J, Feng J, Li Y, Kwan A, Kaye A. Spatiotemporal Organization of Prefrontal Norepinephrine Influences Neuronal Activity. ENeuro 2024, 11: eneuro.0252-23.2024. PMID: 38702188, PMCID: PMC11134306, DOI: 10.1523/eneuro.0252-23.2024.Peer-Reviewed Original ResearchTwo-photon imagingLocus coeruleusPrefrontal cortexOptical flow analysisIn vivo two-photon imagingInfluence neuronal activityVesicle exocytosisControl of cortical activityNE releaseGPCR-based sensorsNE dynamicsLocal fieldNeuronal calciumNeuronal firingCell firingNE roleNorepinephrineHomogeneous fieldNeuronal activitySpatiotemporal activity patternsNeurotransmitter functionSensorLight-sheet imagingAxonal dynamicsSpatial scales