2009
Impact of Chronic Kidney Disease on Early (30-Day) and Late (1-Year) Outcomes of Patients With Acute Coronary Syndromes Treated With Alternative Antithrombotic Treatment Strategies An ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Substudy
Mehran R, Nikolsky E, Lansky AJ, Kirtane AJ, Kim YH, Feit F, Manoukian S, Moses JW, Ebrahimi R, Ohman EM, White HD, Pocock SJ, Dangas GD, Stone GW. Impact of Chronic Kidney Disease on Early (30-Day) and Late (1-Year) Outcomes of Patients With Acute Coronary Syndromes Treated With Alternative Antithrombotic Treatment Strategies An ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Substudy. JACC Cardiovascular Interventions 2009, 2: 748-757. PMID: 19695543, DOI: 10.1016/j.jcin.2009.05.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAdultAgedAged, 80 and overAngioplasty, Balloon, CoronaryBiomarkersChronic DiseaseCoronary Artery BypassCreatinineDrug Therapy, CombinationFemaleFibrinolytic AgentsHemorrhageHeparinHirudinsHumansKidney DiseasesLogistic ModelsMaleMiddle AgedMyocardial InfarctionMyocardial IschemiaOdds RatioPeptide FragmentsPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexProspective StudiesRecombinant ProteinsRisk AssessmentTime FactorsTreatment OutcomeTriageConceptsGlycoprotein IIb/IIIa inhibitorsChronic kidney diseaseAcute coronary syndromeBivalirudin monotherapyComposite ischemiaMajor bleedingCoronary syndromeClinical outcomesKidney diseaseHigh-risk acute coronary syndromesIIb/IIIa inhibitorsClinical adverse outcomesCreatinine clearance dataOutcomes of patientsNormal renal functionAdverse event ratesAntithrombotic treatment strategiesSignificant differencesACUITY trialIschemic outcomesRenal functionAdverse outcomesInvasive strategyLate outcomesTreatment strategies
2003
Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction
Sadeghi HM, Stone GW, Grines CL, Mehran R, Dixon SR, Lansky AJ, Fahy M, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Turco M, Carroll JD. Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. Circulation 2003, 108: 2769-2775. PMID: 14638545, DOI: 10.1161/01.cir.0000103623.63687.21.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAcute DiseaseAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalContrast MediaCoronary RestenosisCreatinineFemaleHumansImmunoglobulin Fab FragmentsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPredictive Value of TestsPrognosisProspective StudiesRenal InsufficiencyRisk AssessmentStentsSurvival RateTreatment OutcomeConceptsPrimary percutaneous coronary interventionAcute myocardial infarctionBaseline renal insufficiencyRenal insufficiencyBaseline CrClMyocardial infarctionPrimary PCIPeripheral vascular diseasePowerful independent predictorPercutaneous coronary interventionRisk of mortalityTransfusion requirementsHemorrhagic complicationsPrimary angioplastySevere restenosisArtery reocclusionCoronary interventionCreatinine clearanceSymptom onsetHeart failureIndependent predictorsAMI patientsCerebrovascular diseasePoor prognosisPrognostic importance
2001
Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure
Gruberg L, Dangas G, Mehran R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure. Catheterization And Cardiovascular Interventions 2001, 55: 66-72. PMID: 11793497, DOI: 10.1002/ccd.10103.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseChronic renal failurePercutaneous coronary interventionClinical outcomesLate mortalityRenal dysfunctionCoronary interventionRenal failureRenal functionRenal diseaseHigher left ventricular ejection fractionNon-Q-wave myocardial infarctionLeft ventricular ejection fractionAngiographic success rateImpaired renal functionNormal renal functionVentricular ejection fractionHospital mortalityCreatinine clearanceConsecutive patientsDiabetes mellitusEjection fractionIndependent correlatesMyocardial infarctionLarge cohort