Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: the PROSPECT study.
Ruiz-García J, Lerman A, Weisz G, Maehara A, Mintz GS, Fahy M, Xu K, Lansky AJ, Cristea E, Farah TG, Teles R, Botker HE, Templin B, Zhang Z, de Bruyne B, Serruys PW, Stone GW. Age- and gender-related changes in plaque composition in patients with acute coronary syndrome: the PROSPECT study. EuroIntervention 2012, 8: 929-38. PMID: 23253546, DOI: 10.4244/eijv8i8a142.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsAcute coronary syndromeNon-culprit lesionsUntreated non-culprit lesionsCoronary syndromePlaque burdenIncidence of MACEAge groupsObstructive coronary artery diseaseNecrotic coreGreater plaque burdenLarger plaque volumeAdverse cardiac eventsCoronary artery diseaseRadiofrequency intravascular ultrasoundYears of ageSame age groupGender-specific differencesSex-related effectsCardiac eventsArtery diseaseAdverse outcomesAtherosclerosis developmentCoronary plaquesGender-related changes