2010
A Risk Score to Predict Bleeding in Patients With Acute Coronary Syndromes
Mehran R, Pocock SJ, Nikolsky E, Clayton T, Dangas GD, Kirtane AJ, Parise H, Fahy M, Manoukian SV, Feit F, Ohman ME, Witzenbichler B, Guagliumi G, Lansky AJ, Stone GW. A Risk Score to Predict Bleeding in Patients With Acute Coronary Syndromes. Journal Of The American College Of Cardiology 2010, 55: 2556-2566. PMID: 20513595, DOI: 10.1016/j.jacc.2009.09.076.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAngioplasty, Balloon, CoronaryCause of DeathConfidence IntervalsCoronary AngiographyCoronary Artery BypassElectrocardiographyFemaleFibrinolytic AgentsHemorrhageHeparinHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexPredictive Value of TestsProbabilityProportional Hazards ModelsRisk AssessmentSeverity of Illness IndexSurvival AnalysisTreatment OutcomeConceptsAcute coronary syndromeInteger risk scoreMajor bleedingRisk scoreCoronary syndromeNon-coronary artery bypass graft surgerySubsequent mortalityCox proportional hazards regression modelArtery bypass graft surgeryProportional hazards regression modelsMultivariable logistic regression modelHORIZONS-AMI trialPractical risk scoreBypass graft surgerySimple risk scoreIndependent baseline predictorsTreatment-related variablesHazards regression modelsAppropriate treatment strategyLogistic regression modelsGraft surgeryHemorrhagic complicationsIdentifies patientsBlood transfusionLarge hematoma
2005
Prediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction The CADILLAC Risk Score
Halkin A, Singh M, Nikolsky E, Grines CL, Tcheng JE, Garcia E, Cox DA, Turco M, Stuckey TD, Na Y, Lansky AJ, Gersh BJ, O’Neill W, Mehran R, Stone GW. Prediction of Mortality After Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction The CADILLAC Risk Score. Journal Of The American College Of Cardiology 2005, 45: 1397-1405. PMID: 15862409, DOI: 10.1016/j.jacc.2005.01.041.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCIAcute myocardial infarctionBaseline left ventricular functionOne-year mortalityPercutaneous coronary interventionLeft ventricular functionRisk scoreCoronary interventionVentricular functionMyocardial infarctionCADILLAC risk scoreExcellent prognostic accuracyPrevious risk scoresStrata of riskAccurate risk stratificationLong-term mortalitySimple risk scoreRespective odds ratiosPrediction of mortalityRisk score modelTime of interventionInitial multivariate modelInteger scoring systemAngiographic variables
2004
A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary interventionDevelopment and initial validation
MEHRAN R, AYMONG E, NIKOLSKY E, LASIC Z, IAKOVOU I, FAHY M, MINTZ G, LANSKY A, MOSES J, STONE G. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary interventionDevelopment and initial validation. Journal Of The American College Of Cardiology 2004, 44: 1393-1399. DOI: 10.1016/s0735-1097(04)01445-7.Peer-Reviewed Original ResearchA simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation
Mehran R, Aymong E, Nikolsky E, Lasic Z, Iakovou I, Fahy M, Mintz G, Lansky A, Moses J, Stone G, Leon M, Dangas G. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation. Journal Of The American College Of Cardiology 2004, 44: 1393-1399. PMID: 15464318, DOI: 10.1016/j.jacc.2004.06.068.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyPercutaneous coronary interventionSimple risk scoreRisk scoreRate of CINRisk of CINCandidate univariate predictorsMultivariate logistic regressionTotal risk scoreGood discriminative powerWeighted integerCoronary interventionIndependent predictorsUnivariate predictorsRisk factorsOdds ratioProcedural characteristicsCumulative riskPatientsLogistic regressionIntervention developmentOverall occurrenceInvestigational purposesNephropathyScores