2022
Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.Peer-Reviewed Original ResearchConceptsSpontaneous coronary artery dissectionPatient Health Questionnaire-9Coronary artery dissectionPSS-14 scoreArtery dissectionBaseline PHQ-9 scoreAcute myocardial infarction patientsCardiovascular risk factorsPHQ-9 scoresAcute myocardial infarctionMyocardial infarction patientsYears of agePerceived Stress Scale scoresStress Scale scoresLinear mixed-effects analysisSCAD casesVIRGO StudyQuestionnaire-9Infarction patientsMixed-effects analysisMyocardial infarctionSubgroup analysisRisk factorsRoutine screeningClinical acuity
2021
Atrial fibrillation risk in patients suffering from type I diabetes mellitus. A review of clinical and experimental evidence
Vrachatis DA, Papathanasiou KA, Kossyvakis C, Giotaki SG, Raisakis K, Iliodromitis KE, Reimers B, Stefanini GG, Cleman M, Sianos G, Lansky A, Deftereos SG, Giannopoulos G. Atrial fibrillation risk in patients suffering from type I diabetes mellitus. A review of clinical and experimental evidence. Diabetes Research And Clinical Practice 2021, 174: 108724. PMID: 33647332, DOI: 10.1016/j.diabres.2021.108724.Peer-Reviewed Original ResearchConceptsDiabetes mellitusAtrial fibrillationType 1 diabetes mellitusIndependent risk factorAtrial fibrillation managementAtrial fibrillation riskAF developmentInsulin deficiencyGlycemic variabilityRisk factorsClinical dataClinical studiesMicrovascular sequelaeAtrial arrhythmogenesisAnimal studiesAtrial myocytesClinical practiceArrhythmia initiationStructural remodelingClinical implicationsT1DMOxidative stressPI3KGlucose transportationMellitus
2020
Does the operator's sex matter? An analysis based on the national interventional cardiology registry.
Lanocha M, Lansky A, Siudak Z, Włodarczak A, Tarchalski J, Malinowski KP, Laskowski W, Sikora T, Radziszewska E, Dolecka-Ślusarczyk M, Wojakowski W, Bartuś S, Grygier M, Tokarek T, Dudek D, Lesiak M. Does the operator's sex matter? An analysis based on the national interventional cardiology registry. Kardiologia Polska 2020, 78: 1221-1226. PMID: 33146499, DOI: 10.33963/kp.15665.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionPractice patternsOutcomes of PCIInterventional cardiologyInterventional Cardiology RegistryCardiovascular risk factorsAcute coronary syndromeSingle-vessel diseaseCoronary artery interventionInvasive cardiology proceduresSex matterMale operatorsCardiology RegistryCoronary syndromeCoronary interventionArtery interventionMore patientsClinical outcomesMain indicationsNational registryRisk factorsMedian numberContrast dosesLow prevalenceHigh doses
2019
Validation of the all-comers design: Results of the TARGET-AC substudy
G Toth G, Lansky A, Baumbach A, Kelbæk H, van Royen N, Holmvang L, Janssens L, Brugaletta S, Barbato E, Maillard L, Kiemeneij F, Naber CK, Pucher F, Laursen PN, Ameloot K, Robles C, Milkas A, Sevilla J, Jensen C, Wijns W. Validation of the all-comers design: Results of the TARGET-AC substudy. American Heart Journal 2019, 221: 148-154. PMID: 31924299, DOI: 10.1016/j.ahj.2019.10.019.Peer-Reviewed Original ResearchConceptsComers designRisk factorsNon-ST elevation acute coronary syndromeElevation acute coronary syndromeNER groupReal-world clinical practiceGroup more patientsInternational multicentre registrySignificant valvular diseaseST-elevation infarctionAcute coronary syndromeChronic total occlusionWorld clinical practiceLow inclusion rateMulticentre registryThrombotic stenosisCoronary syndromePrimary PCIStable anginaAngiographic parametersComers populationPatient demographicsStable patientsStudy nursesMore patients
2017
What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Kuijt WJ, Green CL, Verouden NJW, Haeck JDE, Tzivoni D, Koch KT, Stone GW, Lansky AJ, Broderick S, Tijssen JGP, de Winter RJ, Roe MT, Krucoff MW. What is the best ST-segment recovery parameter to predict clinical outcome and myocardial infarct size? Amplitude, speed, and completeness of ST-segment recovery after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Journal Of Electrocardiology 2017, 50: 952-959. PMID: 29153151, DOI: 10.1016/j.jelectrocard.2017.04.009.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionST-segment recoveryPrimary percutaneous coronary interventionPercutaneous coronary interventionElevation myocardial infarctionInfarct sizeCoronary interventionMyocardial infarctionHolter ECG monitoringMyocardial infarct sizeSingle photon emissionMultivariable adjustmentClinical outcomesRisk factorsClinical trialsNoninvasive biomarkersCore laboratoryMechanistic correlatesMortalityECG monitoringInfarctionRecovery parametersST parametersInterventionOutcomes
2013
Pre-hypertension: another 'pseudodisease’?
Meier P, Messerli FH, Baumbach A, Lansky AJ. Pre-hypertension: another 'pseudodisease’? BMC Medicine 2013, 11: 211. PMID: 24229371, PMCID: PMC3848832, DOI: 10.1186/1741-7015-11-211.Peer-Reviewed Original ResearchConceptsBlood pressureCardiovascular riskRisk factorsCommon cardiovascular risk factorsCardiovascular risk factorsEnd-organ damageIndependent risk factorRisk markersHealthy peopleHypertensionBMC MedicineMmHgPseudodiseaseExpert CommitteeSignificant proportionSignificant markersRiskMarkersSystolicPatientsDisease
2011
Low Stent Thrombosis Risk with the XIENCE V® Everolimus‐Eluting Coronary Stent: Evidence from Randomized and Single‐Arm Clinical Trials
BEZENEK S, HERMILLER J, LANSKY A, YAQUB M, HATTORI K, CAO S, SOOD P, SUDHIR K. Low Stent Thrombosis Risk with the XIENCE V® Everolimus‐Eluting Coronary Stent: Evidence from Randomized and Single‐Arm Clinical Trials. Journal Of Interventional Cardiology 2011, 24: 326-341. PMID: 21443551, DOI: 10.1111/j.1540-8183.2011.00628.x.Peer-Reviewed Original ResearchConceptsEverolimus-Eluting Coronary Stent SystemDual antiplatelet therapyXIENCE VST ratesRisk factorsLow stent thrombosis ratesSingle-arm clinical trialOccurrence of STStent thrombosis riskAcademic Research ConsortiumStent thrombosis ratesPotential risk factorsCoronary stent systemLow ST ratesHigh compliance rateSPIRIT FIRSTAntiplatelet therapyThrombosis rateSPIRIT trialComplex patientsThrombosis riskClinical trialsStent systemThin strut designDrug usage
2010
Selection Criteria for Drug-Eluting Versus Bare-Metal Stents and the Impact of Routine Angiographic Follow-Up 2-Year Insights From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial
Stone GW, Parise H, Witzenbichler B, Kirtane A, Guagliumi G, Peruga JZ, Brodie BR, Dudek D, Möckel M, Lansky AJ, Mehran R. Selection Criteria for Drug-Eluting Versus Bare-Metal Stents and the Impact of Routine Angiographic Follow-Up 2-Year Insights From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial. Journal Of The American College Of Cardiology 2010, 56: 1597-1604. PMID: 20888162, DOI: 10.1016/j.jacc.2010.08.608.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPaclitaxel-eluting stentsBare metal stentsDrug-eluting stentsElevation myocardial infarctionRisk factorsMyocardial infarctionClinical benefitVersus Bare-Metal StentsAbsolute incremental benefitHORIZONS-AMI trialBaseline risk factorsReference vessel diameterAngiographic Follow-upAbsolute treatment effectLesion revascularizationTLR proceduresTLR rateDiabetes mellitusIndependent predictorsRisk strataFollow-upRisk groupsHigh riskAntirestenotic properties
2005
Gender Differences in Outcomes After Primary Angioplasty Versus Primary Stenting With and Without Abciximab for Acute Myocardial Infarction
Lansky AJ, Pietras C, Costa RA, Tsuchiya Y, Brodie BR, Cox DA, Aymong ED, Stuckey TD, Garcia E, Tcheng JE, Mehran R, Negoita M, Fahy M, Cristea E, Turco M, Leon MB, Grines CL, Stone GW. Gender Differences in Outcomes After Primary Angioplasty Versus Primary Stenting With and Without Abciximab for Acute Myocardial Infarction. Circulation 2005, 111: 1611-1618. PMID: 15811868, DOI: 10.1161/01.cir.0000160362.55803.40.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPrimary stentingAddition of abciximabBody surface areaCADILLAC trialMyocardial infarctionRisk factorsFemale genderIschemic target vessel revascularizationLower body surface areaMajor adverse cardiac eventsOverall adverse outcomesTIMI grade 3Adverse cardiac eventsTarget vessel revascularizationClinical risk factorsComorbid risk factorsInterventional treatment strategiesImportant independent determinantHigh mortality rateMACE ratePrimary angioplastyCardiac eventsSymptom onsetIndependent predictorsLow hematocrit predicts contrast-induced nephropathy after percutaneous coronary interventions
Nikolsky E, Mehran R, Lasic Z, Mintz GS, Lansky AJ, Na Y, Pocock S, Negoita M, Moussa I, Stone GW, Moses JW, Leon MB, Dangas G. Low hematocrit predicts contrast-induced nephropathy after percutaneous coronary interventions. Kidney International 2005, 67: 706-713. PMID: 15673320, DOI: 10.1111/j.1523-1755.2005.67131.x.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyPercutaneous coronary interventionBaseline hematocritCoronary interventionLow hematocritLower baseline hematocritChronic kidney diseaseGlomerular filtration rateImportant risk factorBaseline eGFRHematocrit dropLower eGFRConsecutive patientsIndependent predictorsKidney diseaseFiltration rateLowest quintileRisk factorsNephropathyPatientsHematocrit changesMultivariate analysisSignificant associationHematocrit valuesHematocrit
2004
Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions
Nikolsky E, Mehran R, Aymong ED, Mintz GS, Lansky AJ, Lasic Z, Negoita M, Fahy M, Pocock SJ, Na Y, Krieger S, Moses JW, Stone GW, Leon MB, Dangas G. Impact of anemia on outcomes of patients undergoing percutaneous coronary interventions. The American Journal Of Cardiology 2004, 94: 1023-1027. PMID: 15476616, DOI: 10.1016/j.amjcard.2004.06.058.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionMortality rateSmaller body mass indexImpact of anemiaCardiovascular risk factorsOutcomes of patientsCo-morbid conditionsBody mass indexHigh mortality rateWorld Health OrganizationConsecutive patientsBaseline hematocritMass indexPotential confoundersRisk factorsAnemiaPatientsHealth OrganizationSignificant predictorsInterventionHospitalizationConfoundersHigh frequencyHematocritA simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation
Mehran R, Aymong E, Nikolsky E, Lasic Z, Iakovou I, Fahy M, Mintz G, Lansky A, Moses J, Stone G, Leon M, Dangas G. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention Development and initial validation. Journal Of The American College Of Cardiology 2004, 44: 1393-1399. PMID: 15464318, DOI: 10.1016/j.jacc.2004.06.068.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyPercutaneous coronary interventionSimple risk scoreRisk scoreRate of CINRisk of CINCandidate univariate predictorsMultivariate logistic regressionTotal risk scoreGood discriminative powerWeighted integerCoronary interventionIndependent predictorsUnivariate predictorsRisk factorsOdds ratioProcedural characteristicsCumulative riskPatientsLogistic regressionIntervention developmentOverall occurrenceInvestigational purposesNephropathyScores
2001
Effect of gender on the outcomes of contemporary percutaneous coronary intervention
Peterson E, Lansky A, Kramer J, Anstrom K, Lanzilotta M, Investigators F. Effect of gender on the outcomes of contemporary percutaneous coronary intervention. The American Journal Of Cardiology 2001, 88: 359-364. PMID: 11545754, DOI: 10.1016/s0002-9149(01)01679-4.Peer-Reviewed Original ResearchConceptsIndependent risk factorRisk factorsBaseline clinical risk factorsHigher vascular complication ratesContemporary percutaneous coronary interventionPercutaneous coronary intervention (PCI) technologyRisk adjustmentExtensive coronary diseaseProcedural mortality rateVascular complication ratesClinical risk factorsPercutaneous coronary interventionBody surface areaPatient body sizeHospital revascularizationAssociation of genderComorbid illnessesVascular complicationsComplication rateCoronary interventionCoronary diseaseProcedural outcomesFemale genderIndependent riskPCI cases