2012
A New Score for Risk Stratification of Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention The ACUITY-PCI (Acute Catheterization and Urgent Intervention Triage Strategy–Percutaneous Coronary Intervention) Risk Score
Palmerini T, Genereux P, Caixeta A, Cristea E, Lansky A, Mehran R, Della Riva D, Fahy M, Xu K, Stone GW. A New Score for Risk Stratification of Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention The ACUITY-PCI (Acute Catheterization and Urgent Intervention Triage Strategy–Percutaneous Coronary Intervention) Risk Score. JACC Cardiovascular Interventions 2012, 5: 1108-1116. PMID: 23174634, DOI: 10.1016/j.jcin.2012.07.011.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute coronary syndromeCoronary artery diseaseRisk scoreRisk stratificationCoronary syndromeCoronary interventionArtery diseaseElectrocardiographic variablesSegment elevation acute coronary syndromesElevation acute coronary syndromeDiffuse coronary artery diseaseCardiac biomarker elevationClinical SYNTAX scoreEarly invasive strategyGRACE risk scoreTIMI risk scoreInsulin-treated diabetesNet reclassification improvementNew scoreBetter prognostic accuracyST-segment deviationACUITY trialAngiographic substudyRenal insufficiency
2007
An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary intervention.
Nikolsky E, Pucelikova T, Mehran R, Balter S, Kaufman L, Fahy M, Lansky AJ, Leon MB, Moses JW, Stone GW, Dangas G. An evaluation of fluoroscopy time and correlation with outcomes after percutaneous coronary intervention. Journal Of Invasive Cardiology 2007, 19: 208-13. PMID: 17476034.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAngioplasty, Balloon, CoronaryCohort StudiesCoronary AngiographyCoronary Artery BypassCoronary DiseaseElectrocardiographyFemaleFluoroscopyFollow-Up StudiesHospital MortalityHumansLinear ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProbabilityRetrospective StudiesRisk FactorsSensitivity and SpecificitySeverity of Illness IndexSurvival RateTime FactorsTreatment OutcomeConceptsCoronary artery bypass surgeryPercutaneous coronary interventionEmergent coronary artery bypass surgeryPrior coronary artery bypass surgeryProlonged fluoroscopy timeContrast-induced nephropathyPeripheral arterial diseaseFluoroscopy timeBaseline TIMICoronary interventionArterial diseaseComplexity of PCIType B2/C lesionsB2/C lesionsSevere lesion calcificationChronic renal insufficiencyArtery bypass surgeryShort-term prognosisMean fluoroscopy timeHospital deathHospital outcomesPeriprocedural complicationsRenal insufficiencyBypass surgeryLesion calcification
2005
Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease
Lansky AJ, Costa RA, Mooney M, Midei MG, Lui HK, Strickland W, Mehran R, Leon MB, Russell ME, Ellis SG, Stone GW, Investigators T. Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease. Journal Of The American College Of Cardiology 2005, 45: 1180-1185. PMID: 15837246, DOI: 10.1016/j.jacc.2004.10.076.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationPaclitaxel-eluting stent implantationIndependent predictorsStent implantationTaxus stentPaclitaxel-eluting Taxus stentElective coronary interventionTAXUS-IV trialOnly independent predictorCoronary artery diseaseOne-year ratesGender-based outcomesBare metal stentsLesion revascularizationMore hypertensionAngiographic restenosisRenal insufficiencyCoronary interventionUnstable anginaArtery diseaseHeart failureRestenosis rateLess smokingFemale genderLate loss
2003
Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction
Sadeghi HM, Stone GW, Grines CL, Mehran R, Dixon SR, Lansky AJ, Fahy M, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Turco M, Carroll JD. Impact of Renal Insufficiency in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. Circulation 2003, 108: 2769-2775. PMID: 14638545, DOI: 10.1161/01.cir.0000103623.63687.21.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAcute DiseaseAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalContrast MediaCoronary RestenosisCreatinineFemaleHumansImmunoglobulin Fab FragmentsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPredictive Value of TestsPrognosisProspective StudiesRenal InsufficiencyRisk AssessmentStentsSurvival RateTreatment OutcomeConceptsPrimary percutaneous coronary interventionAcute myocardial infarctionBaseline renal insufficiencyRenal insufficiencyBaseline CrClMyocardial infarctionPrimary PCIPeripheral vascular diseasePowerful independent predictorPercutaneous coronary interventionRisk of mortalityTransfusion requirementsHemorrhagic complicationsPrimary angioplastySevere restenosisArtery reocclusionCoronary interventionCreatinine clearanceSymptom onsetHeart failureIndependent predictorsAMI patientsCerebrovascular diseasePoor prognosisPrognostic importanceMarked mortality risk of renal insufficiency in patients undergoing primary angioplasty for acute myocardial infarction
Sadeghi H, Grines C, Mehran R, Dixon S, Lansky A, Fahy M, Cox D, Garcia E, Tcheng J, Griffin J, Guagliumi G, Stuckey T, Turco M, Carroll J, Rutherford B, Stone G. Marked mortality risk of renal insufficiency in patients undergoing primary angioplasty for acute myocardial infarction. Journal Of The American College Of Cardiology 2003, 41: 384. DOI: 10.1016/s0735-1097(03)81097-5.Peer-Reviewed Original Research
2001
Intravascular Ultrasound—Guided Renal Artery Stenting
Dangas G, Laird J, Mehran R, Lansky A, Mintz G, Leon M. Intravascular Ultrasound—Guided Renal Artery Stenting. Journal Of Endovascular Therapy 2001, 8: 238-247. PMID: 11491257, DOI: 10.1177/152660280100800302.Peer-Reviewed Original ResearchConceptsRenal arteryDiastolic arterial blood pressureLesion lengthHospital renal failureMean contrast volumePalmaz stent implantationRenal artery revascularizationRenal artery stentingStenotic renal arteriesArterial blood pressureIntravascular ultrasound guidanceMinimal luminal diameterProximal renal arteriesMajority of lesionsMean lesion lengthAntihypertensive medicationsArtery revascularizationTransient hemodialysisUncontrolled hypertensionAngiographic successRenal insufficiencyRenal failureSerum creatinineArtery stentingBlood pressureIntravascular Ultrasound–Guided Renal Artery Stenting
Dangas G, Laird J, Mehran R, Lansky A, Mintz G, Leon M. Intravascular Ultrasound–Guided Renal Artery Stenting. Journal Of Endovascular Therapy 2001, 8: 238-247. DOI: 10.1583/1545-1550(2001)008<0238:iugras>2.0.co;2.Peer-Reviewed Original ResearchRenal arteryDiastolic arterial blood pressureLesion lengthHospital renal failureMean contrast volumePalmaz stent implantationRenal artery revascularizationRenal artery stentingStenotic renal arteriesArterial blood pressureIntravascular ultrasound guidanceMinimal luminal diameterProximal renal arteriesMajority of lesionsMean lesion lengthAntihypertensive medicationsArtery revascularizationTransient hemodialysisUncontrolled hypertensionAngiographic successRenal insufficiencyRenal failureSerum creatinineArtery stentingBlood pressure
2000
The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency
Gruberg L, Mintz G, Mehran R, Dangas G, Lansky A, Kent K, Pichard A, Satler L, Leon M. The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. Journal Of The American College Of Cardiology 2000, 36: 1542-1548. PMID: 11079656, DOI: 10.1016/s0735-1097(00)00917-7.Peer-Reviewed Original ResearchConceptsRenal function deteriorationFurther renal function deteriorationOne-year mortalityFunction deteriorationCoronary interventionCreatinine increaseHospital mortalityRenal insufficiencyRenal functionSerum creatinineIndependent predictorsPre-existing renal insufficiencyHospital clinical eventsBaseline serum creatinineChronic renal insufficiencyLong-term mortalityTertiary referral centerPercutaneous coronary interventionVentricular ejection fractionInterventional coronary proceduresChronic dialysisCreatinine elevationAcute deteriorationReferral centerConsecutive patients