2008
Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis
Kim YH, Dangas GD, Solinas E, Aoki J, Parise H, Kimura M, Franklin-Bond T, Dasgupta NK, Kirtane AJ, Moussa I, Lansky AJ, Collins M, Stone GW, Leon MB, Moses JW, Mehran R. Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis. The American Journal Of Cardiology 2008, 101: 801-806. PMID: 18328844, DOI: 10.1016/j.amjcard.2007.10.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary StenosisElectrocardiographyFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMyocardial RevascularizationPaclitaxelProspective StudiesSirolimusStentsTreatment OutcomeTubulin ModulatorsUltrasonography, InterventionalConceptsHigh surgical riskMain coronary artery stenosisMajor adverse cardiac eventsUnprotected LMCA stenosisAdverse cardiac eventsCoronary artery stenosisSurgical riskLMCA stenosisCardiac eventsArtery stenosisStent thrombosisMyocardial infarctionBifurcation stenosisUnprotected left main coronary artery stenosisLeft main coronary artery stenosisDrug-eluting stent placementUrgent percutaneous coronary interventionQ-wave myocardial infarctionFeasible therapeutic alternativeOutcomes of patientsPercutaneous coronary interventionPaclitaxel-eluting stentsSingle-stent strategyUnfavorable clinical outcomeSirolimus-eluting stents
2006
Treatment of Coronary Artery Perforations Complicating Percutaneous Coronary Intervention With a Polytetrafluoroethylene-Covered Stent Graft
Lansky AJ, Yang YM, Khan Y, Costa RA, Pietras C, Tsuchiya Y, Cristea E, Collins M, Mehran R, Dangas GD, Moses JW, Leon MB, Stone GW. Treatment of Coronary Artery Perforations Complicating Percutaneous Coronary Intervention With a Polytetrafluoroethylene-Covered Stent Graft. The American Journal Of Cardiology 2006, 98: 370-374. PMID: 16860026, DOI: 10.1016/j.amjcard.2006.02.041.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary stent graftEmergency coronary bypass surgeryQ-wave myocardial infarctionCoronary bypass surgeryCoronary interventionCoronary perforationStent graftBypass surgeryMyocardial infarctionOverall procedure success rateReversal of anticoagulationLife-threatening complicationsCoronary artery perforationProcedure success rateStent-graft implantationAbrupt vessel closureEffective treatment optionProlonged balloon inflationMulticenter seriesCardiogenic shockArtery perforationPericardial tamponadeCardiac arrestTreatment options
2004
Comparison of differences in outcome after percutaneous coronary intervention in men versus women <40 years of age
Lansky AJ, Mehran R, Dangas G, Cristea E, Shirai K, Costa R, Costantini C, Tsuchiya Y, Carlier S, Mintz G, Cottin Y, Stone G, Moses J, Leon MB. Comparison of differences in outcome after percutaneous coronary intervention in men versus women <40 years of age. The American Journal Of Cardiology 2004, 93: 916-919. PMID: 15050498, DOI: 10.1016/j.amjcard.2003.12.046.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionYears of ageCoronary interventionVascular complicationsMyocardial infarctionMortality rateAggressive risk factor modificationQ-wave myocardial infarctionHospital vascular complicationsMore diabetes mellitusPredominance of diabetesNonfatal myocardial infarctionRisk factor modificationPremature coronary diseaseRisk factor profileOnly independent predictorMultivariable regression analysisLess hyperlipidemiaIschemic complicationsConsecutive patientsCoronary diseaseDiabetes mellitusIndependent predictorsPremature atherosclerosisFactor modificationMinimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease
Shirai K, Lansky AJ, Mehran R, Dangas GD, Costantini CO, Fahy M, Slack S, Mintz GS, Stone GW, Leon MB. Minimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease. The American Journal Of Cardiology 2004, 93: 959-962. PMID: 15081435, DOI: 10.1016/j.amjcard.2003.12.048.Peer-Reviewed Original ResearchConceptsCoronary artery bypassInvasive coronary artery bypassLAD stentingCoronary artery diseaseArtery bypassArtery diseaseClinical outcomesAnterior descending (LAD) coronary artery diseaseConventional coronary artery bypassHigher repeat revascularization ratesQ-wave myocardial infarctionHospital event ratesProximal LAD diseaseRepeat revascularization rateShorter hospital staySubgroup of patientsConventional balloon angioplastyIncidence of deathLong-term efficacyLAD revascularizationMIDCAB groupHospital stayLAD diseaseRevascularization ratesVessel revascularization
2001
Differential Impact on Survival of Electrocardiographic Q-Wave Versus Enzymatic Myocardial Infarction After Percutaneous Intervention
Stone G, Mehran R, Dangas G, Lansky A, Kornowski R, Leon M. Differential Impact on Survival of Electrocardiographic Q-Wave Versus Enzymatic Myocardial Infarction After Percutaneous Intervention. Circulation 2001, 104: 642-647. PMID: 11489768, DOI: 10.1161/hc3101.093902.Peer-Reviewed Original ResearchConceptsQ-wave myocardial infarctionMyocardial infarctionPercutaneous interventionCPK-MB elevationNon-Q-wave myocardial infarctionElective percutaneous interventionIndependent research nurseSerial creatine phosphokinasePeriprocedural myocardial infarctionTertiary referral centerRelative prognostic importanceNew Q wavesCPK-MB levelsPowerful independent determinantCPK-MB releaseEnzymatic elevationPeriprocedural infarctionReferral centerConsecutive patientsReferral populationResearch nursesIndependent determinantsPrognostic importanceStent useQ waves
2000
Percutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes
Gruberg L, Dangas G, Mehran R, Hong M, Waksman R, Mintz G, Kent K, Pichard A, Satler L, Lansky A, Stone G, Leon M. Percutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes. Journal Of The American College Of Cardiology 2000, 35: 944-948. PMID: 10732892, DOI: 10.1016/s0735-1097(99)00652-x.Peer-Reviewed Original ResearchConceptsInternal mammary artery graftMammary artery graftsIMA graftsPercutaneous revascularizationBalloon angioplastyArtery graftClinical outcomesProcedural successMyocardial infarctionOne-year clinical outcomesLong-term clinical outcomesQ-wave myocardial infarctionAlternative interventional techniquesLower TLR rateUrgent bypass surgeryHigh procedural successLong-term outcomesTreatment of stenosisLong-term resultsOne-year ratesHospital complicationsHospital outcomesTLR rateAnastomotic lesionsBypass surgeryProcedural results and late clinical outcomes after percutaneous interventions using long (≥25 mm) versus short (<20 mm) stents
Kornowski R, Bhargava B, Fuchs D, Lansky A, Satler L, Pichard A, Hong M, Kent K, Mehran R, Stone G, Leon M. Procedural results and late clinical outcomes after percutaneous interventions using long (≥25 mm) versus short (<20 mm) stents. Journal Of The American College Of Cardiology 2000, 35: 612-618. PMID: 10716462, DOI: 10.1016/s0735-1097(99)00580-x.Peer-Reviewed Original ResearchConceptsShort stent groupsPeriprocedural non-Q-wave myocardial infarctionNon-Q-wave myocardial infarctionCardiac event-free survivalEvent-free survivalMyocardial infarctionClinical outcomesProcedural successStent groupShort stentsHospital complicationsLesion revascularizationLong stentsOverall cardiac event-free survivalLong-term clinical outcomesQ-wave myocardial infarctionLate clinical outcomesLong stent implantationsMajor procedural complicationsMean stent lengthMore diffuse lesionsSingle-vessel interventionVessel revascularization rateOverall procedural successLong-term outcomes
1999
Intracoronary radiation for patients with refractory in-stent restenosis An analysis from the wrist-crossover trial
Waksman R, Bhargava B, White R, Chan R, Gierlach L, Mehran R, Lansky A, Kent K, Mintz G, Satler L, Pichard A, Leon M. Intracoronary radiation for patients with refractory in-stent restenosis An analysis from the wrist-crossover trial. Cardiovascular Revascularization Medicine 1999, 1: 317-322. PMID: 10828560, DOI: 10.1016/s1522-1865(00)00024-x.Peer-Reviewed Original ResearchConceptsPrimary treatment groupTarget lesion revascularizationCrossover groupStent restenosisTreatment groupsClinical trialsQ-wave myocardial infarctionStent restenosis TrialAdverse cardiac eventsPrimary clinical endpointIntracoronary stent implantationRandomized clinical trialsCatheter-based interventionsCatheter-based techniquesStent neointimal formationAnginal symptomsLesion revascularizationRecurrent ISRRestenosis TrialActive therapyAngiographic outcomesCardiac eventsPlacebo armProcedural successIntracoronary radiationPreintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention
Dangas G, Mintz G, Mehran R, Lansky A, Kornowski R, Pichard A, Satler L, Kent K, Stone G, Leon M. Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention. Circulation 1999, 99: 3149-3154. PMID: 10377078, DOI: 10.1161/01.cir.99.24.3149.Peer-Reviewed Original ResearchConceptsIndependent predictorsArterial remodelingTarget lesion revascularization rateInsulin-dependent diabetic patientsLong-term clinical outcomesQ-wave myocardial infarctionMultivariable logistic regression analysisTarget lesion revascularizationShort-term complicationsIntravascular ultrasound studyLong-term outcomesFinal lumen areaLogistic regression analysisIntermediate remodelingAngiographic characteristicsAngiographic successRevascularization ratesCoronary interventionClinical outcomesDiabetic patientsPlaque burdenPositive remodelingMyocardial infarctionNegative remodelingPercutaneous intervention