The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency
Gruberg L, Mintz G, Mehran R, Dangas G, Lansky A, Kent K, Pichard A, Satler L, Leon M. The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. Journal Of The American College Of Cardiology 2000, 36: 1542-1548. PMID: 11079656, DOI: 10.1016/s0735-1097(00)00917-7.Peer-Reviewed Original ResearchConceptsRenal function deteriorationFurther renal function deteriorationOne-year mortalityFunction deteriorationCoronary interventionCreatinine increaseHospital mortalityRenal insufficiencyRenal functionSerum creatinineIndependent predictorsPre-existing renal insufficiencyHospital clinical eventsBaseline serum creatinineChronic renal insufficiencyLong-term mortalityTertiary referral centerPercutaneous coronary interventionVentricular ejection fractionInterventional coronary proceduresChronic dialysisCreatinine elevationAcute deteriorationReferral centerConsecutive patientsRandomized Trial of Contrast Media Utilization in High-Risk PTCA
Davidson C, Laskey W, Hermiller J, Harrison J, Matthai W, Vlietstra R, Brinker J, Kereiakes D, Muhlestein J, Lansky A, Popma J, Buchbinder M, Hirshfeld J. Randomized Trial of Contrast Media Utilization in High-Risk PTCA. Circulation 2000, 101: 2172-2177. PMID: 10801758, DOI: 10.1161/01.cir.101.18.2172.Peer-Reviewed Original ResearchConceptsMajor adverse clinical eventsHospital major adverse clinical eventsPrimary end pointClinical eventsNonionic dimer iodixanolDimer iodixanolEnd pointLow-osmolar contrast agentsHigh-risk PTCAHospital clinical eventsThrombus-related eventsTotal clinical eventsDouble-blind trialAcute coronary syndromeHigh-risk patientsProspective multicenter trialAdverse clinical eventsCoronary artery interventionPTCA outcomeAngiographic successCoronary syndromeNovo lesionsArtery interventionMulticenter trialRandomized trials