2024
Approval, Evidence, and “Off-Label” Device Utilization: The Patent Foramen Ovale Closure Story
Goldsweig A, Deng Y, Yao X, Desai N, Cohen D, Aronow H, Messé S, Ross J, Lansky A, Savitz S. Approval, Evidence, and “Off-Label” Device Utilization: The Patent Foramen Ovale Closure Story. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010200. PMID: 38189127, PMCID: PMC10844981, DOI: 10.1161/circoutcomes.123.010200.Peer-Reviewed Original ResearchStroke/systemic embolismTransient ischemia attackPFO closureSystemic embolismIschemia attackRetrospective cohort studyTransient ischemic attackHalf of patientsOptumLabs Data WarehouseCommercial insurance enrolleesRegulatory approvalClinical trial publicationsIschemic attackRecurrent strokeCohort studyPatent foramenUnderwent closureAtrial fibrillationClinical trialsInsurance enrolleesDecompression illnessTrial publicationsOff labelPatientsProcedure volume
2021
The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction.
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S, Dalby MC, Malik IS, Whitbread M, Firoozi S, Bogle R, Redwood S, Cooper J, Gupta A, Lansky A, Wragg A, Mathur A, Ahluwalia A. The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction. Am J Cardiovasc Dis 2021, 11: 659-678. PMID: 34849299, PMCID: PMC8611266.Peer-Reviewed Original ResearchST-segment elevation myocardial infarctionCause mortalityFemale sexCox analysisMyocardial infarctionST-elevation myocardial infarctionAge-matched menObservational cohort studyElevation myocardial infarctionPercutaneous coronary interventionKaplan-Meier analysisLong-term outcomesProportional hazards modelSub-group analysisHigh mortality rateYears of agePost-PCIPrimary PCICoronary interventionSTEMI patientsCohort studyMultivariate adjustmentPrimary outcomeUnivariate predictorsMenopausal yearsWall shear stress estimated by 3D-QCA can predict cardiovascular events in lesions with borderline negative fractional flow reserve
Tufaro V, Safi H, Torii R, Koo BK, Kitslaar P, Ramasamy A, Mathur A, Jones DA, Bajaj R, Erdoğan E, Lansky A, Zhang J, Konstantinou K, Little CD, Rakhit R, Karamasis GV, Baumbach A, Bourantas CV. Wall shear stress estimated by 3D-QCA can predict cardiovascular events in lesions with borderline negative fractional flow reserve. Atherosclerosis 2021, 322: 24-30. PMID: 33706080, DOI: 10.1016/j.atherosclerosis.2021.02.018.Peer-Reviewed Original ResearchConceptsNegative fractional flow reserveCardiovascular eventsFractional flow reservePrimary endpointFlow reserveSmaller minimum lumen areaAdverse cardiovascular eventsRetrospective cohort studyTarget lesion revascularizationOnly independent predictorMinimum lumen areaQCA variablesAngiographic characteristicsLesion revascularizationCulprit lesionHighest maximum wall shear stressCohort studyCardiac deathIndependent predictorsComplete followMultivariable analysisMyocardial infarctionTarget lesionsArea stenosisNegative FFR
2020
Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race
Kim Y, Park J, Essa M, Lansky AJ, Sugeng L. Frequency of Management of Cardiogenic Shock With Mechanical Circulatory Support Devices According to Race. The American Journal Of Cardiology 2020, 125: 1782-1787. PMID: 32471549, DOI: 10.1016/j.amjcard.2020.03.025.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMechanical circulatory supportCardiogenic shockNational Inpatient SampleHospital mortalityBlack patientsInpatient SampleMCS devicesPopulation-based retrospective cohort studyMCS utilizationMechanical circulatory support devicesOnly black patientsRetrospective cohort studyClinical Modification codesMultivariate logistic regressionCirculatory support devicesAcute clinical scenariosHospital outcomesCohort studyPrimary outcomeClinical outcomesHospital eventsCirculatory supportNinth RevisionMyocardial infarction