2013
Three-year clinical results of the Axxess Biolimus A9 eluting bifurcation stent system: the DIVERGE study.
Buysschaert I, Dubois CL, Dens J, Ormiston J, Worthley S, McClean D, Ottervanger JP, Meredith I, Uren N, Wijns W, Whitbourn R, Mehran R, Lansky AJ, Bichalska M, Meis S, Verheye S. Three-year clinical results of the Axxess Biolimus A9 eluting bifurcation stent system: the DIVERGE study. EuroIntervention 2013, 9: 573-81. PMID: 24058075, DOI: 10.4244/eijv9i5a93.Peer-Reviewed Original ResearchConceptsTarget lesion revascularisationIschaemia-driven target lesion revascularisationMajor adverse cardiac eventsSecondary safety endpointStent thrombosisMyocardial infarctionBifurcation lesionsAXXESS stentSafety endpointClinical outcomesBiolimus A9De novo coronary bifurcation lesionsThree-year clinical outcomesNew-generation drug-eluting stentsThree-year clinical resultsCumulative stent thrombosisProbable ST eventsAdverse cardiac eventsSingle-arm trialImproved clinical outcomesTrue bifurcation lesionsCoronary bifurcation lesionsDrug-eluting stentsPromising treatment strategyPresent large study
2009
9-Month Clinical, Angiographic, and Intravascular Ultrasound Results of a Prospective Evaluation of the Axxess Self-Expanding Biolimus A9-Eluting Stent in Coronary Bifurcation Lesions The DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) Study
Verheye S, Agostoni P, Dubois CL, Dens J, Ormiston J, Worthley S, Trauthen B, Hasegawa T, Koo BK, Fitzgerald PJ, Mehran R, Lansky AJ. 9-Month Clinical, Angiographic, and Intravascular Ultrasound Results of a Prospective Evaluation of the Axxess Self-Expanding Biolimus A9-Eluting Stent in Coronary Bifurcation Lesions The DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) Study. Journal Of The American College Of Cardiology 2009, 53: 1031-1039. PMID: 19298915, DOI: 10.1016/j.jacc.2008.12.012.Peer-Reviewed Original ResearchConceptsPercent neointimal volume obstructionMajor adverse cardiac eventsNeointimal volume obstructionCoronary bifurcation lesionsBifurcation lesionsAXXESS stentVolume obstructionMulticenter studyMyocardial infarctionLate lossParent vesselDe novo bifurcation lesionsEnd pointIntravascular ultrasound resultsNovo bifurcation lesionsAdverse cardiac eventsComposite of deathPrimary end pointSecondary end pointsProspective multicenter studySirolimus-eluting stentsAdverse late outcomesSide branchesDrug-eluting stentsLate stent thrombosis
2007
Six-Month Clinical and Angiographic Results of a Dedicated Drug-Eluting Stent for the Treatment of Coronary Bifurcation Narrowings
Grube E, Buellesfeld L, Neumann FJ, Verheye S, Abizaid A, McClean D, Mueller R, Lansky A, Mehran R, Costa R, Gerckens U, Trauthen B, Fitzgerald PJ. Six-Month Clinical and Angiographic Results of a Dedicated Drug-Eluting Stent for the Treatment of Coronary Bifurcation Narrowings. The American Journal Of Cardiology 2007, 99: 1691-1697. PMID: 17560877, DOI: 10.1016/j.amjcard.2007.01.043.Peer-Reviewed Original ResearchConceptsCoronary bifurcation lesionsBifurcation lesionsDe novo coronary bifurcation lesionsProspective multicenter single-arm studyBiolimus A9-eluting stentMulticenter single-arm studyResult of restenosisTarget lesion revascularizationClinical complication rateSingle-arm studyStent late lossSide branchesDrug-eluting stentsLate stent thrombosisBalloon angioplasty treatmentLesion revascularizationNonbifurcation lesionsAntiplatelet therapyComplication rateAngiographic resultsStent thrombosisBalloon angioplastyPercutaneous interventionAngioplasty treatmentAXXESS stent