2024
Uterine teratoma and the role of short-tandem repeat genotyping in understanding origins
AlAshqar A, Maruthi V, Abi-Raad R, Greenman M, Hui P, Ratner E, Altwerger G, Santin A, Andikyan V. Uterine teratoma and the role of short-tandem repeat genotyping in understanding origins. Gynecologic Oncology Reports 2024, 56: 101652. DOI: 10.1016/j.gore.2024.101652.Peer-Reviewed Original ResearchUterine teratomaPluripotent stem cellsMolecular testingRare tumorLimitations of diagnostic imagingHistory of vaginal bleedingShort tandem repeat genotypingStem cellsAdvanced molecular testingRepeat genotypingFallopian tube tissueGerm cell layersLoss of heterozygosityFour-week historyVaginal bleedingSurgical resectionOvarian counterpartRare entityUterine massPrimiparous womenEndometrial samplesFetal tissuesTeratomaPresence of tissueDiploid karyotype
2014
Identification of Optimal Reference Genes for Gene Expression Normalization in a Wide Cohort of Endometrioid Endometrial Carcinoma Tissues
Romani C, Calza S, Todeschini P, Tassi RA, Zanotti L, Bandiera E, Sartori E, Pecorelli S, Ravaggi A, Santin AD, Bignotti E. Identification of Optimal Reference Genes for Gene Expression Normalization in a Wide Cohort of Endometrioid Endometrial Carcinoma Tissues. PLOS ONE 2014, 9: e113781. PMID: 25473950, PMCID: PMC4256201, DOI: 10.1371/journal.pone.0113781.Peer-Reviewed Original ResearchMeSH KeywordsActinsAdultAgedAged, 80 and overCarcinoma, EndometrioidCohort StudiesEndometriumFemaleGene Expression Regulation, NeoplasticGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)HumansMiddle AgedNeoplasm StagingOvarian NeoplasmsReal-Time Polymerase Chain ReactionReference ValuesRNARNA, Ribosomal, 18SSoftwareConceptsEndometrial cancer tissuesEndometrial cancer samplesEndometrial carcinoma tissuesHigh-grade tumorsNormal endometrial tissuesEndometrial tumor samplesReal-time RT-PCRGreen real-time RT-PCRSYBR Green real-time RT-PCRTumor degreeEndometrial tissueEndometrial samplesTumor gradeUse of PPIAStudy groupHPRT1 expressionQRT-PCR techniqueCancer tissuesCarcinoma tissuesWider cohortTumor samplesCancer samplesRT-PCRExpression levelsSignificant differences